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Table 2 Comparison of different diagnostic tests for patients with active tuberculosis infection at University of Texas MD Anderson Cancer Center from 2006 to 2014

From: Active Mycobacterium tuberculosis infection at a comprehensive cancer center, 2006–2014

Patients

Without cancer diagnosis

N = 20 (%)

With cancer diagnosis

N = 32 (%)

Positive AFB smear

5 (25)

6 (19)

Positive TB Culture

20 (100)

32 (100)

Sputum

1 (5)

6 (19)

BAL

6 (30)

9 (28)

FNA

2 (10)

9 (28)

Tissue

11 (55)

8 (25)

Positive TB PCRa

1

1

Positive IGRA

7/8b (88)

9/16c (56)

T-SPOT.TB

0

1

QFT.TB

7

8

Negative IGRA

1/8b (13)

3/16c (19)

T-SPOT.TB

1

0

QTF.TB

0

3

Inconclusive IGRA

0

4/16c (25)

T-SPOT.TB

0

0

QTF.TB

0

4

  1. a 3 TB PCR were performed
  2. b 8 in non-cancer patients
  3. c 16 cancer patients
  4. Abbreviations: AFB, Acid fast bacilli; TB, tuberculosis; BAL, bronchoalveolar lavage; FNA, fine needle aspirate; PCR, polymerase chain reaction; IGRA, interferon gamma release assay; QFT, QuantiFERON