Years | 1978–79 | 1994–95 |
---|---|---|
Number of patients | 50 | 30 |
Sex M/F (index) | 28/22 (1.3) | 18/13 (1.4) |
Median age (range) | 32 (23–85) | 25 (15–78) |
HBeAg positive (%) | 34 (68.0) | 17 (56.7) |
HBeAg negative (%) | 16 (32.0) | 13 (43.3) |
Anti-HBe positive (%) | 29 (58.0) | 17 (56.7) |
Mean Log10 HBV DNA (range) | 5.51 (3.29–8.51) | 4.34 (1.48–8.71) |
Anti-HDV positive (%) | 2 (4.0) | 3 (10.0) |
Anti-HCV positive (%) | 12 (24.0) | 8 (25.8) |
Mean hospital days (range) | 37.6 (18–77) | 19.5 (8–26) |
Mean IU ALT (range) | 2280 (850–3760) | 2678 (658–4600) |
Risk exposure: | ||
IDU (%) | 4/50 (8.0) § | 8/30 (26.7) § |
other parenteral (sexual, household contact) (%) | 20/50 (40.0) | 7/30 (23.3) |
unknown (%) | 26/50 (52.0) | 16/30 (53.3) |
HBV genotype (%): | ||
A | 6/50 (12.0) | 6/30 (20.0) |
D | 43/50 (86.0) | 24/30 (80.0) |
E | 1/50 (2.0) | – |
HBV-D sub-genotype (%) a | ||
D1 | 1/29 (3.4) | 1/16 (6.2) |
D2 | 3/29 (10.3) | 2/16 (12.5) |
D3 | 25/29 (86.2) | 13/16 (81.2) |