Table 1 Baseline characteristics of observed patients
From: Burden of Staphylococcus aureus infections after orthopedic surgery in Germany
Characteristic | All observed patients | Patients with a hip surgery | Patients with a knee surgery | Patients with a spine surgery | Patients with SAI in the 365-d follow-up | Patients w/o SAI in the 365-d follow-up | p-value for differences between patients with/without SAI |
|---|---|---|---|---|---|---|---|
N | 74,327 | 29,429 | 21,285 | 23,613 | 1430 | 72,897 | |
Age in years; Mean (SD) | 69.59 (13.41) | 74.09 (11.63) | 70.39 (9.56) | 63.25 (15.79) | 74.97 (11.54) | 69.48 (18.42) | p < 0.001 |
Female sex; N (%) | 45,771 (61.58) | 18,912 (64.26) | 13,915 (65.37) | 12,944 (54.82) | 781 (54.62) | 44,990 (61.72) | p < 0.001 |
CCI (12-month baseline period); Mean (SD) | 2.28 (2.42) | 2.48 (2.48) | 2.15 (2.15) | 2.14 (2.56) | 3.76 (2.95) | 2.25 (2.40) | p < 0.001 |
Length of index hospitalization in days; Mean (SD) | 14.07 (9.12) | 15.37 (9.08) | 13.12 (6.04) | 13.29 (11.09) | 20.05 (15.27) | 13.95 (8.92) | p < 0.001 |
Type of index surgery | |||||||
Primary surgery; N (%) | 45,706 (61.49) | 26,427 (89.80) | 19,279 (90.58) | – | 816 (57.06) | 44,890 (61.58) | p < 0.001 |
Revisional/exchange/removal surgery; N (%) | 3874 (5.21) | 2265 (7.70) | 1609 (7.56) | – | 116 (8.11) | 3758 (5.12) | p < 0.001 |
Unspecifieda; N (%) | 1134 (1.53) | 737 (2.50) | 397 (1.87) | – | 36 (2.52) | 1098 (1.51) | p = 0.002 |
Spinal fusion; N(%) | 6554 (8.82) | – | – | 6554 (27.76) | 139 (9.72) | 6415 (8.80) | p = 0.224 |
Other spine surgeries; N(%) | 17,059 (22.95) | – | – | 17,059 (72.24) | 323 (22.59) | 16,736 (22.96) | p = 0.741 |
Complications due to prosthetic devices/ implants/grafts during index hospitalization; N (%) | 4298 (5.78) | 2405 (8.17) | 1730 (8.13) | 163 (0.69) | 131 (9.16) | 4167 (5.72) | p < 0.001 |
Recent fractures at the location of index surgery (3 months baseline period); N (%) | 16,123 (21.69) | 8963 (30.46) | 592 (2.78) | 6568 (27.82) | 627 (43.85) | 15,496 (21.26) | p < 0.001 |
Bacterial infections (not caused by any Staphylococci) during index hospitalization; N (%) | 4091 (5.50) | 2142 (7.28) | 644 (3.03) | 1305 (5.53) | 208 (14.55) | 3883 (5.33) | p < 0.001 |
Outpatient prescriptions of antibiotics (12 months baseline period); Mean (SD) | 0.60 (1.18) | 0.56 (1.17) | 0.61 (1.14) | 0.64 (1.24) | 0.84 (1.57) | 0.60 (1.17) | p < 0.001 |
Follow-up period within 365 days follow-up in days, censored at; Mean (SD) | |||||||
Death | 351.34 (61.32) | 341.98 (79.29) | 362.33 (26.45) | 353.09 (56.11) | 324.46 (88.71) | 351.86 (60.54) | p < 0.001 |
Death or infection date | 347.95 (67.65) | 337.93 (84.89) | 359.81 (36.66) | 349.74 (62.93) | 148.23 (101.97) | 351.86 (60.54) | p < 0.001 |
Death, infection date or date of any next surgery not performed at the same body location as index surgery | 318.28 (100.74) | 313.66 (107.17) | 335.05 (80.22) | 308.93 (107.07) | 120.93 (94.73) | 322.15 (96.92) | p < 0.001 |