Table 2 Cytomegalovirus infection during pregnancy, and potential impact of screening or a prevention program promoting hygiene. Figures are numbers (%) for the best and minimal and maximum; % are provided with one decimal when > 1%, two decimals when ≤1% but > 0.1%, and three decimals when ≤0.1%.
State | Current situation | Screening | Promotion of hygiene | ||||||
|---|---|---|---|---|---|---|---|---|---|
Best (%) | Minimum (%) | Maximum (%) | Best (%) | Minimum (% | Maximum (%) | Best (%) | Minimum (% | Maximum (%) | |
CMV seronegative | 435,200 (54.4) | 598,400 (74.8) | 312,000 (39.0) | 433,683 (54.2) | 595,414 (74,4) | 310,128 (38,8) | 435,200 (54.4) | 598,400 (74.8) | 312,000 (39.0) |
MPI | 4352 (0.54) | 1197 (0.15) | 4368 (0.55) | 3018 (0.38) | 1270 (0.16) | 3069 (0.38) | 2176 (0.27) | 598 (0.07) | 2184 (0.27) |
Foetal infection in CMV- | 1741 (0.22) | 60 (0.0008) | 3154 (0.39) | 1741 (0.22) | 60 (0.008) | 3154 (0.39) | 870 (0.11) | 30 (0.004) | 1577 (0.20) |
CMV seropositive | 364,800 (49.6) | 201,600 (25.2) | 488,000 (61.0) | 366,317 (45.8) | 204,586 (25.6) | 488,408 (61,1) | 364,800 (45.6) | 201,600 (25.2) | 488,000 (61.0) |
Foetal infection after RI | 1699 (0.21) | 1540 (0.19) | 1726 (0.22) | 1699 (0.21) | 1540 (0.19) | 1726 (0.22) | 1699 (0.21) | 1540 (0.19) | 1726 (0.22) |
Total foetal infections | 3440 (0.43) | 1600 (0.20) | 4880 (0.61) | 3440 (0.43) | 1600 (0.20) | 4880 (0.61) | 2569 (0.32) | 1570 (0.20) | 3303 (0.41) |
Deaths & TOP | 316 0.040) | 147 (0.018) | 449 (0.056) | 919 (0.12) | 183 (0.023) | 1968 (0.25) | 236 (0.030) | 144 (0.018) | 304 (0.038) |
Total congenital infections | 3123 (0.39) | 1453 (0.18) | 4431 (0.55) | 2522 (0.32) | 1417 (0.18) | 2913 (0.36) | 2333 (0.29) | 1425 (0.18) | 2999 (0.37) |
Symptomatic in RI | 60 (0.008) | 54 (0.007) | 60 (0.008) | 60 (0.008) | 54 (0.007) | 60 (0.008) | 60 (0.008) | 54 (0.007) | 60 (0.008) |
Symptomatic in MPI | 60 (0.008) | 2 (< 0.001) | 110 (0.014) | 41 (0.005) | 1 (< 0.001) | 61 (0.008) | 30 (0.004) | 1 (< 0.001) | 55 (0.007) |
Severe symptomatic | 60 (0.008) | 28 (0.004) | 85 (0.011) | 50 (0.006) | 27 (0,003) | 60 (0.008) | 45 (0.006) | 27 (0,003) | 58 (0.007) |
Moderate symptomatic | 60 (0.008) | 28 (0.004) | 85 (0.011) | 50 (0.006) | 27 (0,003) | 60 (0.008) | 45 (0.006) | 27 (0,003) | 58 (0.007) |
Sequelae asymptom. RI | 197 (0.025) | 179 (0.022) | 200 (0.025) | 197 (0.025) | 179 (0.022) | 200 (0.025) | 197 (0.025) | 179 (0.022) | 200 (0.025) |
Sequelae asymptom. MPI | 202 (0.025) | 7 (< 0.001) | 366 (0.05) | 125 (0.016) | 2 (< 0.001) | 171 (0,022) | 101 (0.013) | 3 (< 0.001) | 183 (0.023) |
Severe sequela (symptom) | 48 (0.006) | 22 (0.003) | 68 (0.009) | 40 (0.005) | 22 (0.003) | 48 (0.006) | 36 (0.005) | 22 (0.003) | 46 (0.006) |
Mod. sequelae (symptom) | 35 (0.004) | 11 (0.001) | 35 (0.004) | 21 (0.003) | 11 (0.001) | 25 (0.003) | 18 (0.002) | 11 (0.001) | 24 (0.003) |
Total poor outcomes | 788 (0.099) | 367 (0.046) | 1119 (0.14) | 1301 (0.16) | 397 (0.050) | 2413 (0.30) | 588 (0.074) | 356 (0.045) | 757 (0.095) |