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Table 2 Bayesian analysis of the positive and negative results

From: Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay

 

Specificity (%)

90

96

99

Sensitivity (%)a

99

99

99

Prevalenceb

1/150

1/150

1/150

Negative predictive value

0.999

0.999

0.999

Positive predictive value

0.07

0.14

0.41

  1. a assumed for the purposes of this analysis and is based on the reported sensitivity of a rigorously-designed bacterium-specific qPCR assay [6]
  2. b prevalence amongst babies tested for meningitis as based on our practice [15]
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BMC Infectious Diseases

ISSN: 1471-2334

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