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Table 1 Radiology findings and interpretation of cases and controls

From: Radiographic features in investigated for Pneumocystis jirovecii pneumonia: a nested case-control study

 

Univariable

Multivariable

X-ray Finding (%)

Cases (N = 69)

Controls (N = 270)

P-Value

Odds Ratio

(95% CI)

Increased interstitial markings

33 (47.8)

50 (18.5)

0.0001

2.9 (1.6–5.1)

Pleural Effusion

13 (18.8)

72 (26.7)

0.18

Airspace Disease

12 (17.4)

70 (25.9)

0.14

Atelectasis

10 (14.3)

44 (16.3)

0.68

Consolidation

8 (11.6)

43 (15.9)

0.37

Ground glass infiltrate

8 (11.6)

12 (4.4)

0.02

Reticulo-nodular opacities

7 (10.1)

30 (11.1)

0.82

Pulmonary edema

6 (8.7)

37 (13.7)

0.26

Normal

1 (1.4)

14 (5.2)

0.18

Radiologist PCP Possible/Likely

12 (17.4)

12 (4.4)

0.0001

4.5 (1.8–10.9)

CT Finding (%)

Cases (N = 64)

Controls (N = 231)

P-Value

Odds Ratio

(95% CI)

Ground glass opacity

61 (95.3)

154 (66.7)

0.0001

3.3 (1.2–9.1)

Interstitial markings

30 (46.9)

39 (16.8)

0.0001

4.3 (2.2–8.2)

Adenopathy

30 (46.9)

91 (39.2)

0.27

Septal thickening

21 (32.8)

69 (29.7)

0.64

Consolidation

17 (26.6)

65 (28)

0.82

Pleural Effusion

16 (25)

97 (41.8)

0.01

Nodular findings

15 (23.4)

104 (45)

0.0001

Emphysema/bullae

12 (18.8)

31 (13.4)

0.28

Linear-reticular opacities

5 (7.8)

1 (0.4)

0.0001

Cavitary lesion

5 (7.8)

7 (3)

0.09

Cystic changes

3 (4.7)

8 (3.4)

0.64

Mass lesion

1 (1.6)

3 (1.3)

0.87

Pulmonary embolism

1 (1.6)

3 (1.3)

0.87

Airspace disease

0 (0)

17 (7.3)

0.03

Pneumomediastinum

0 (0)

5 (2.2)

0.24

Crazy paving

0 (0)

7 (3)

0.16

Small airway thickening

0 (0)

5 (2.2)

0.24

Pneumothorax

0 (0)

2 (0.9)

0.46

Honeycombing

0 (0)

1 (0.4)

0.6

Radiologist - PCP Possible

21 (32.8)

50 (21.6)

0.06

2.0 (1.0–4.1)

Radiologist - PCP Likely

16 (25)

8 (3.4)

0.0001

9.3 (3.4–25.3)

  1. Sorted by descending prevalence in PCP. Data is expressed as the number and percentage of total reports in which these findings appeared in. Ground glass infiltrates or opacities refers to a nonspecific finding on computed tomography (CT) scans wherein there is partial filling of air spaces in the lungs, as well as interstitial thickening or partial collapse of lung alveoli. May be seen diffusely in the lung; “ground glass” indicating 1–2 mm. Reticulonodular opacities or linear-reticular opacities refers to overlaying of reticular shadows (irregular linear opacities) and this can also be seen in the presence of pulmonary nodules. Crazy paving refers to the appearance of ground-glass opacities with superimposed inter and intralobular septal thickening and intralobular septal thickening. Honeycombing is seen with widespread fibrosis; small cystic spaces are observed with irregularly thickened walls made up of fibrous tissue