A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis

BMC Infectious Diseases

Table 1 Characteristics of the included studies

Author	Year	Country	Patients (n)	Specimen	Referencestandard	TP	FP	FN	TN
McKenna et al .[12]	2011	UK	139	Throat swab	PCR	12	1	0	126
McKenna et al .[12]	2011	UK	141	Serum	PCR	14	1	0	126
McKenna et al .[12]	2011	UK	72	Blood	PCR	4	1	0	67
McKenna et al .[12]	2011	UK	22	CSF	PCR	3	1	0	18
McKenna et al .[12]	2011	UK	16	Respiratory secretions	PCR	2	0	0	14
McKenna et al .[12]	2011	UK	4	Feces	PCR	1	0	0	3
Bourke et al .[13]	2015	U.K.	141	Nasopharyngeal	PCR	21	0	4	116
Bourke et al .[13]	2015	U.K.	144	Blood	PCR	22	0	4	118
Lee et al .[14]	2015	South Korea	31	CSF	Culture	2	3	0	26
Lee et al .[15]	2015	South Korea	568	CSF	PCR	15	5	0	548
Lee et al .[15]	2015	South Korea	536	CSF	PCR	5	0	0	531
Lee et al .[15]	2015	South Korea	470	CSF	PCR	5	1	0	464
Takahashi et al .[16]	2016	Japan	836	Throat swab	PCR	6	1	0	829
Higgins et al .[17]	2018	UK	65	Blood	PCR	22	0	0	43

CSF cerebrospinal fluid, FN false negative, FP false positive, TN true negative, TP true positive

ISSN: 1471-2334