Table 2 Clinical characteristics of 12 maternal listeriosis cases
From: Perinatal listeriosis patients treated at a maternity hospital in Beijing, China, from 2013–2018
No | Gestation (wk) | Obstetrical manifestations | Culture sites | Initial antibiotic | Switched antibiotic | Maternal complications and outcomes | |||
|---|---|---|---|---|---|---|---|---|---|
Maternal blood | Placental tissue | Cervical secretion | Others | ||||||
1 | 31.3 | decreased fetal movement 3d; fetal distress; Tmax:39.3 °C | (−) | (+) | / | / | metronidazole + amoxicillin 4d | No | premature delivery; C-section; severe meconium staining of amniotic fluid; recovered |
2 | 24.4 | decreased fetal movement 3d; lower abdominal pain; twin pregnancy; PROM; Tmax:38.5 °C | (−) | (+) | (+) | / | cefuroxime 3d | No | stillbirth; recovered |
3 | 20.0 | abdominal pain; fetal movement disappear 3d; chill; Tmax:38.7 °C | (−) | (+) | (−) | hydrothorax, ascite, amniotic fluid (+) | amoxicillin 3d | No | inevitable miscarriage; induced labor; recovered |
4 | 34.3 | decreased fetal movement 1d; uterine contraction; fetal distress; headache; Tmax:38.8 °C | (−) | (+) | (−) | / | cefmetazole 1d | moxifloxacin 6d | premature delivery; severe meconium staining of amniotic fluid; recovered |
5 | 26.0 | lower abdominal pain 17 h; PROM; fetal distress; septicemia; Tmax:39 °C | (+) | (+) | (−) | / | cefuroxime 3d | metronidazole 3d | stillbirth; induced labor; recovered |
6 | 36.1 | decreased fetal movement 2d; fetal distress; polyhydramnios; Tmax:38 °C | (−) | (+) | / | / | cefuroxime 3d | No | premature delivery; C-section; severe meconium staining of amniotic fluid; recovered |
7 | 38.1 | fetal distress; Tmax:39.2 °C | (−) | (+) | / | / | metronidazole + ceftriaxone 4d | No | normal labor; postpartum hemorrhage; C-section; severe meconium staining of amniotic fluid; recovered |
8 | 21.7 | fever15d; intrauterine fetal death1d; lower abdominal pain; headache; Tmax:39.1 °C | (−) | (+) | (−) | / | cefuroxime 8d + cefdinir 5d | moxifloxacin 6d | inevitable miscarriage; induced labor; recovered |
9 | 35.6 | fetal distress; threatened prematurity; twin pregnancy; septicemia; Tmax:38.4 °C | (+) | (−) | / | / | ceftriaxone 5d | No | premature delivery; postpartum hemorrhage; recovered |
10 | 24.9 | fever7d; fetal distress; abdominal pain; septicemia; Tmax:39.3 °C | (+) | (+) | (−) | / | ceftriaxone 7d | PNG 4d | stillbirth; recovered |
11 | 35.4 | fetal distress; decreased fetal movement 1d; afebrile | (−) | (+) | / | / | cefuroxime 3d | No | premature delivery; recovered |
12 | 27.3 | fever 2w; prematurity; vaginal bleeding; uterine contraction; septicemia; Tmax:39 °C | (+) | (+) | (−) | / | clindamycin + ceftriaxone 2d | azithromycin + PNG 7d | premature delivery; postpartum hemorrhage; C-section; mild meconium staining of amniotic fluid; recovered |