# | Statement | View 1 | View 2 |
---|---|---|---|
1 | Combination therapy of intralesional sodium stibogluconate and other CL therapy modalities such as cryotherapy, systemic antibiotics are superior to monotherapy with sodium stibogluconate. | + 2* | −1 |
2 | Combination therapy is superior to monotherapy for any case of CL | 0* | −3 |
3 | Effectiveness of combined intralesional sodium stibogluconate or cryotherapy with liquid nitrogen with antibiotics (e.g., Azithromycin or Doxycycline) is mainly due to overcoming secondary bacterial infection by antibiotics. | + 2* | − 3 |
4 | Problems of sodium stibogluconate are interrupted supply to health care providers and lack of original quality sometimes. | + 3* | −1 |
5 | Resistance to treatment in CL is due to low efficacy drugs. | + 2* | + 1 |
6 | The use of herbal or homemade remedies by patients, which interfere with treatment, is very common. | + 3* | −4 |
7 | Patients noncompliance to the schedule of the treatment plan is the main obstacle for treating patients with CL | + 2* | 0 |
8 | Fear of patients from treatment modalities and unawareness about the disease makes them not sticking to treatment schedules and instructions. | + 1* | −1 |
9 | If Zinc sulfate is given as monotherapy in large doses, it can heal CL patients. | −4* | −1 |
10 | Rifampicin is a potent and effective anti- CL treatment. | −2* | 0 |
11 | Systematic antifungal drugs (e.g., ketoconazole or fluconazole) are effective in the treatment of CL. | −1* | 0 |
12 | Debridement and dressing of ulcerated lesions of CL have an important role in the treatment plan. | −3* | −2 |
13 | For CL lesions of up to 4 in number, especially in hidden areas of the body, there is no need for any treatment, and only dressing and tying is enough. | −4* | −3 |
14 | After decades of serious work and the presence of several options with newer compounds and combinations, there is still a little advance in the treatment of CL, which is not satisfactory for both doctors and patients. | −2* | + 2 |
15 | CL course extends more than 1–2 months despite treatment. | 0* | + 3 |
16 | Resistance to treatment is the main complication of CL treatment. | −1* | + 1 |
17 | Cryotherapy with liquid nitrogen is the treatment of choice in children, especially for facial and ear lesions and dry lesions. | −1* | + 3 |
18 | The effect of cryotherapy with liquid nitrogen is unpredictable; some patients benefit from cryotherapy sessions while others come back with blistering and ulceration of lesions. | + 1* | + 2 |
19 | Photodynamic therapy for CL lesions is advised for lesions located on cosmetically concerned areas such as the face. | −1* | + 1 |
20 | The intralesional sodium stibogluconate method is to inject it until the lesion turns white and is indurated. | + 3* | + 4 |
21 | Systemic sodium stibogluconate is given when there is no response to cryotherapy with liquid nitrogen. | −2* | −4 |