Table 3 Characteristics and outcomes of E. coli bUTI patients with and without urinary symptoms or signs
bUTI with urinary symptoms (N = 161) | bUTI without urinary symptoms (N = 123) | p-value | |
|---|---|---|---|
Demographics | |||
Age categories | 0.0025 | ||
< 65 years | 61 (37.9%) | 24 (19.5%) | |
65–74 years | 26 (16.2%) | 22 (17.9%) | |
75–84 years | 44 (27.3%) | 36 (29.3%) | |
> =85 years | 30 (18.6%) | 41 (33.3%) | |
Age median (IQR) | 72.8 (56.0–81.9) | 79.0 (67.5–86.6) | 0.0002 |
Female | 122 (75.8%) | 85 (69.1%) | 0.2271 |
Long term care home | 16 (9.9%) | 28 (22.8%) | 0.0045 |
Admitting service | 0.4445 | ||
Medicine | 147 (91.3%) | 117 (95.1%) | |
Surgery | 12 (7.5%) | 6 (4.9%) | |
ICU | 2 (1.2%) | 0 (0%) | |
Charlson comorbidity score | 0.1632 | ||
0 | 96 (59.6%) | 85 (69.1%) | |
1 | 27 (16.8%) | 12 (9.8%) | |
> =2 | 38 (23.6%) | 26 (21.1%) | |
Charlson comorbidity | |||
Stroke | 10 (6.2%) | 11 (8.9%) | 0.4933 |
Dementia | 7 (4.4%) | 10 (8.1%) | 0.2121 |
Diabetes | 15 (9.3%) | 7 (5.7%) | 0.3706 |
Diabetes with complications | 13 (8.1%) | 3 (2.4%) | 0.0660 |
History of urinary risk factors | |||
Chronic indwelling Foley catheter | 7 (5.7%) | 5 (3.1%) | 0.3745 |
Benign prostate hypertrophy | 5 (3.1%) | 11 (8.9%) | 0.0401 |
Urinary malignancy | 9 (5.6%) | 4 (3.3%) | 0.4041 |
Prior urinary tract infection | 42 (26.1%) | 23 (18.7%) | 0.1559 |
Nephrolithiasis | 14 (8.7%) | 2 (1.6%) | 0.0097 |
Cystoscopy | 6 (3.7%) | 2 (1.6%) | 0.4727 |
Prostate biopsy | 2 (1.2%) | 4 (3.3%) | 0.4083 |
Other urologic procedure | 24 (14.9%) | 13 (10.6%) | 0.3739 |
Severity of Infection | |||
Delirium | 26 (16.2%) | 42 (34.2%) | 0.0007 |
Sepsis by SIRS criteria | 155 (96.3%) | 119 (96.8%) | > 0.9999 |
Sepsis by qSOFA criteria | 53 (32.9%) | 57 (46.3%) | 0.0268 |
Hypotensive shock SBP < 90 | 120 (74.5%) | 103 (83.7%) | 0.0797 |
Transfer to ICU in 72 h | 9 (5.6%) | 10 (8.1%) | 0.4746 |
Empiric antibiotics before blood culture collection | 15 (9.3%) | 9 (7.3%) | 0.6683 |
Outcome | |||
Death in hospital | 5 (3.1%) | 12 (9.8%) | 0.0234 |