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Table 5 Treatment outcomes in patients between group I and group II at 10 weeks

From: Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure

 

Group I (AmB+

Group II (AmB+

P-value

Fluconazole + 5-FC,n = 27)

Fluconazole + 5-FC + VPS, n = 39)

Lost to follow-up

0 (0.0%)

1 (2.3%)

0.399

Successful response

8 (29.6%)

22 (57.9%)

0.025*

 Complete response

3 (11.1%)

11 (28.9%)

 

 Partial response

5 (18.5%)

11 (28.9%)

 

Failure

19 (70.4%)

16 (42.1%)

0.350

 Stable response

15 (55.6%)

10 (26.3%)

 

 Disease progression

4 (14.8%)

4 (10.5%)

 

 Death

0 (0.0%)

2 (5.3%)

 
  1. *p < 0.05