Fig. 2
From: Potential anti-EBV effects associated with elevated interleukin-21 levels: a case report
Time line of clinical history. 2012: pulmonary infiltrates are detected. 2014: An open lung biopsy is performed revealing pronounced EBV activity and histologic signs of B cell transformation. Elevated peripheral EBV copy numbers, mediastinal adenopathy, elevated liver enzymes, CD8+ lymphopenia and hypogammaglobulinemia are also documented and immunologic and genetic work-up commences. 2019: rapidly deteriorating lung function and 30–40 kg weight loss