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Table 6 Comparison of serum cytokines levels across sedentary and non-sedentary groups with different infections

From: Asymptomatic malaria and hepatitis B do not influence cytokine responses of persons involved in chronic sedentary activities

Parameters (pg/mL)

Sedentary groups with different infection status

*p

Sedentary and Infected group

Sedentary and Un-infected

Non-sedentary and Infected group

Non-sedentary and Un-infected group

Pro-inflammatory cytokines

Median (IQR), n

TNF-α

12.95 (10.03–15.59) 13

10.72 (8.55–12.89) 7

9.84 (6.45–11.92) 9

12.69 (7.93–14.51) 4

0.349

IL-1β

3.35 (2.91–4.67) 10

3.91 (1.98–9.58) 5

3.14 (2.36–4.59) 6

4.56 (3.62–5.44) 4

0.615

IL-6

37.63 (26.48–50.68) 13

33.21 (25.49–47.9) 8

27.78 (20.98–36.3) 9

42.01 (21.21–56.59) 3

0.534

IFN-γ

6.89 (3.83–10.18) 17

6.00 (3.86–7.47) 8

6.25 (3.87–8.81) 12

5.52 (2.16–9.92) 4

0.867

IL-8

13.6 (10.25–19.34) 8

47.38 (7.60–395.00) 5

15.93 (7.36–22.12) 5

35.95 (5.36–404.4) 4

0.685

IL-12

4.68 (3.78–5.83) 12

4.12 (2.75–5. 86) 7

4.27 (3.87–5.96) 7

1.99 (1.80–3.54) 4

0.119

Anti-inflammatory cytokines

Median (IQR), n

IL-10

34.4 (23.94–69.84) 13

12.66 (11.82–35.28) 5

16.49 (14.39–27.41) 7

17.37 (11.53–29.71) 4

0.098

IL-7

20.22 (17.72–26.28) 7

17.04 (11.92–20.51) 8

19.24 (10.46–19.76) 3

17.81 (10.53–34.92) 4

0.461

IL-13

30.14 (25.00–36.64) 10

19.65 (15.86–48.81) 5

27.47 (14.63–38.20) 9

23.26 (15.70–34.90) 4

0.852

  1. *; analyzed by Krulskal-Wallis test at < 0.05 level of statistical significance
  2. p significant at < 0.05 (2-tailed)
  3. IQR interquartile range
  4. n number of samples