Fig. 2From: Identifying pre-outbreak signals of hand, foot and mouth disease based on landscape dynamic network markerThe algorithm of landscape dynamic network marker. The flow chart above shows how the algorithm works based on city networks and the historical information of clinic hospitalization. Regarding a point T = t (t > 5) as a candidate tipping point, L-DNM scores can be calculated. If the L-DNM score increases significantly, the candidate T = t is determined as the identified tipping point, and the algorithm ends. Otherwise, if there is no significant change in the score, then T = t is classified as a time point belonging to the normal stage, and the algorithm continues with T = t + 1 being a new candidate tipping pointBack to article page