From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease
Parameter |  | Postoperative infection (n = 279) | Control (n = 5104) | Total (n = 5383) | P value |
---|---|---|---|---|---|
Age (days) | Median (IQR) | 832 (489,1386) | 933 (548,1459.5) | 929 (545,1458) | 0.057^ |
CPB time (min) | Median (IQR) | 88 (66,125) | 48 (36,72) | 49 (36,75) | < 0.001^ |
Aortic clamping time (min) | Median (IQR) | 52 (39,76) | 28 (19,44) | 29 (19,46) | < 0.001^ |
Gender | MALE | 152 (54.48%) | 2828 (55.41%) | 2980 (55.36%) | 0.762# |
Preterm birth | YES | 2 (0.72%) | 37 (0.72%) | 39 (0.72%) | > 0.999## |
History of cardiac surgery | YES | 82 (29.39%) | 673 (13.19%) | 755 (14.03%) | < 0.001# |
BMI | < 5th percentile | 77 (29.84%) | 748 (15.83%) | 825 (16.56%) | < 0.001# |
5th–95th percentile | 174 (67.44%) | 3734 (79.03%) | 3908 (78.43%) |  | |
> 95th percentile | 7 (2.71%) | 243 (5.14%) | 250 (5.02%) | Â | |
STS risk grade | 1 | 61 (21.86%) | 3064 (60.03%) | 3125 (58.05%) | < 0.001^ |
2 | 144 (51.61%) | 1497 (29.33%) | 1641 (30.48%) | Â | |
3 | 37 (13.26%) | 356 (6.97%) | 393 (7.3%) | Â | |
4 | 34 (12.19%) | 182 (3.57%) | 216 (4.01%) | Â | |
5 | 3 (1.08%) | 5 (0.1%) | 8 (0.15%) | Â | |
Delayed sternal closure | YES | 4 (1.43%) | 8 (0.16%) | 12 (0.22%) | 0.003## |
ALT | < cut off value | 19 (8.23%) | 315 (6.53%) | 334 (6.61%) | < 0.001# |
Normal | 200 (86.58%) | 4435 (91.97%) | 4635 (91.73%) | Â | |
>cut off value | 12 (5.19%) | 72 (1.49%) | 84 (1.66%) | Â | |
AST | Normal | 157 (65.15%) | 3825 (78.13%) | 3982 (77.52%) | < 0.001# |
>cut off value | 84 (34.85%) | 1071 (21.88%) | 1155 (22.48%) | Â | |
ALP | Normal | 240 (99.59%) | 4860 (99.31%) | 5100 (99.32%) | > 0.999## |
>cut off value | 1 (0.41%) | 34 (0.69%) | 35 (0.68%) | Â | |
Serum creatinine | < cut off value | 0 (0%) | 4 (0.08%) | 4 (0.08%) | 0.145## |
Normal | 239 (99.58%) | 4885 (99.88%) | 5124 (99.86%) | Â | |
>cut off value | 1 (0.42%) | 2 (0.04%) | 3 (0.06%) | Â | |
WBC counts | < cut off value | 4 (1.43%) | 30 (0.59%) | 34 (0.63%) | 0.008# |
Normal | 263 (94.27%) | 4970 (97.37%) | 5233 (97.21%) | Â | |
>cut off value | 12 (4.3%) | 104 (2.04%) | 116 (2.15%) | Â | |
Lymphocyte count | < cut off value | 7 (2.51%) | 26 (0.51%) | 33 (0.61%) | < 0.001# |
Normal | 101 (36.2%) | 1537 (30.11%) | 1638 (30.43%) | Â | |
>cut off value | 171 (61.29%) | 3541 (69.38%) | 3712 (68.96%) | Â | |
Neutrophil count | < cut off value | 22 (7.89%) | 445 (8.72%) | 467 (8.68%) | 0.003# |
Normal | 223 (79.93%) | 4311 (84.46%) | 4534 (84.23%) | Â | |
>cut off value | 34 (12.19%) | 348 (6.82%) | 382 (7.1%) | Â | |
Lymphocytes/WBC | < cut off value | 11 (3.94%) | 49 (0.96%) | 60 (1.11%) | < 0.001# |
Normal | 63 (22.58%) | 910 (17.83%) | 973 (18.08%) | Â | |
>cut off value | 205 (73.48%) | 4145 (81.21%) | 4350 (80.81%) | Â | |
Neutrophils/WBC | < cut off value | 209 (74.91%) | 4053 (79.41%) | 4262 (79.18%) | 0.003# |
Normal | 59 (21.15%) | 976 (19.12%) | 1035 (19.23%) | Â | |
>cut off value | 11 (3.94%) | 75 (1.47%) | 86 (1.6%) | Â |