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Table 1 Papers on clinical and eco-epidemiology of paracoccidioidomycosis in Colombia since 2000

From: Thinking in paracoccidioidomycosis: a delayed diagnosis of a neglected tropical disease, case report and review of clinical reports and eco-epidemiologic data from Colombia since the 2000

Year

Type of paper

Details of the study, Clinical and epidemiological characteristics

Ref

2000

Case report

A 24 year-old male farmer with an enlarging mass in the right testicle, retroperitoneal and inguinal nodules, pancreatic infiltration and hepatosplenomegaly due to juvenile PCM. The patient was resident of the rural area of the municipality of Tarso, department of Antioquia.

[19]

2000

Case report

A 55 year-old male with Multifocal PCM, who presented with neurological symptoms and an ulcerated granulomatous lesion in the abdomen. The patient lived in the city of Medellín, department of Antioquia, but in his younger years, was a farmer in a rural region.

[20]

2002

Case series

Six patients with adrenal insufficiency from a registry of 207 patients from the archives of the Corporación para Investigaciones Biológicas (CIB), in Medellín, department of Antioquia. Average age 67.2 years, they were residents of rural area, five of them were farmers and smokers.

[21]

2003

Case series

Follow-up for pulmonary abnormalities in 47 itraconazole-treated patients with PCM. Fibrosis was observed in 31.8% of the patients at diagnosis and developed de novo in 25% of the patients.

[22]

2005

Phylogenetic Study

Determination of at least three distinct species of PCM: S1, PS2, and PS3 (apparently restricted to regions of Colombia).

[23]

2005

Ecological study

First report of P. brasiliensis isolation from the spleen of a naked-tailed armadillo Cabassous centralis captured in a coffee farm localized in a Colombian endemic area for PCM.

[24]

2007

Case report

Autopsy diagnosis of a 63-year-old man patient, resident of the rural area of the municipality of Lebrija, department of Santander, with pulmonary, lymphatic and adrenal PCM.

[25]

2008

Retrospective cohort study

63 patients diagnosed and treated between 1978 and 2005 in the city of Medellín. 65.1% had mucosal lesions, 38.1% had Odynophagia and dysphagia, all patients had lung interstitial infiltrates and fibrosis was recorded in 46%.

[26]

2009

2 cases

Report of two cases of adrenal insufficiency secondary to infiltration of the adrenal glands. The case 2 lived in the city of Medellín, but with a history of previous residence in Venezuela

[27]

2010

Cross-sectional study: 28 patients.

Evaluation of the status of the adrenal gland function after completion of antifungal therapy of patients with PCM who had been treated earlier at the CIB: 7.1% showed adrenal insufficiency. Average age 55.3 years, all were male patients, 39.3% were farmers and 85.7% were smokers, 60.7% had chronic multifocal form, 21.4% had sub-acute form, and 17.9% had the chronic unifocal form.

[28]

2010

Case report

A 31-year-old HIV infected male patient, Embera Catío indigenous, resident of rural area of the municipality of Tarazá (department of Antioquia), works as a coca leaf scraper and with a history of smoking; presenting with simultaneous co-infection by Histoplasma capsulatum and Paracoccidioides brasiliensis.

[29]

2011

Case report

56-year-old male with Multifocal chronic PCM, residing in an urban area of the city of Cali (department of Valle del Cauca); he had emigrated from a wooded region of the city of Pasto (department of Nariño) where he performed agricultural and carpentry tasks.

[30]

2011

Case series

A descriptive case series study aimed at determining the type and frequency of opportunistic diseases in HIV/AIDS patients: 1 case with co-infection by P. brasiliensis.

[31]

2014

Case report

A 12-year-old woman with disseminated juvenile PCM diagnosed in an urban area of Bogotá, Colombia.

[32]

2015

Case report

A 69-year-old HIV infected male patient with a CD4 T-cell count of 23 cells/mL, presenting with Cutaneous PCM. He was a farmer in a rural area of the department of Antioquia.

[33]

2016

Case report

A 10-year-old man from the rural area of the municipality of Yotoco, department of Valle del Cauca, presenting with subacute lymphatic PCM.

[34]

2017

Case report

67-year-old male with pulmonary PCM, resident of the rural area of the municipality of Aratoca, department of Santander, worked as a farmer, with a history of smoking.

[35]

2018

Case report

49-year-old male, coffee grower, from City of Acevedo, department of Huila, with a history of smoking, presenting with Multifocal chronic PCM.

[36]

  1. PCM paracoccidioidomycosis, CIB Corporación para Investigaciones Biológicas