The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study

Table 2 Resistance by ART Status and drug class, North West Province, South Africa, 2014^a

	Analyte Positive^c		ART experienced,^b analyte negative		ART naïve^b		Total
	Percent	95% CI	Percent	95% CI	Percent	95% CI	Percent	95% CI
Genotype result	wgt n^a = 2643		wgt n^a = 677		wgt n^a = 4623		wgt n^a = 7943
No resistance	24.4	14.4–38.3	49.0	10.7–88.4	72.6	55.2–85.1	54.6	43.4–65.4
Any resistance	21.3	9.1–42.4	51.1	11.6–89.3	6.3	2.4–15.5	15.1	8.2–26.3
Genotyping failure	54.3	35.4–72.0	0.0	–	21.1	9.4–40.7	30.3	20.3–42.6
Resistance - among those genotyped	wgt n^a = 1209		wgt n^a = 677		wgt n^a = 3650		wgt n^a = 5536
No resistance	53.4	30.0–75.7	49.0	10.7–88.4	92.0	81.0–96.9	78.3	64.3–87.9
Any resistance	46.6	24.6–70.0	51.1	11.6–89.3	8.0	3.1–18.9	21.7	12.1–35.7
Drug class resistance	wgt n^a = 564		wgt n^a = 346		wgt n^a = 291		wgt n^a = 1201
Single class
NRTI only	0.0	–	0.0	–	0.0	–	0.0	–
NNRTI only	0.0	–	73.1	27.9–95.0	63.0	18.1–92.9	36.3	17.7–60.2
PI only	0.0	–	12.2	1.4–58.6	11.5	1.2–58.0	6.3	1.3–25.7
Dual class
NRTI/NNRTI	100.0	–	14.7	1.6–64.1	0.0	–	51.2	28.3–73.6
PI/NRTI	0.0	–	0.0	–	25.5	3.3–77.6	6.2	0.7–37.3
PI/NNRTI	0.0	–	0.0	–	0.0	–	0.0	–

^aWeights account for sampling, non-response, and age/sex of target population, ^bBy self report, ^c Assessed EFV, LPV, NVP

ISSN: 1471-2334