Table 1 Clinical characteristics of patients in the mucus plug and control group
From: Prediction of risk factors of bronchial mucus plugs in children with Mycoplasma pneumoniae pneumonia
Variables | Mucus plug group (n = 90) | Control group (n = 165) | P value |
|---|---|---|---|
Characteristics | |||
Gender (male/female, n) | 49/41 | 89/76 | 0.938 |
Age (−x ± s)/year | 6.10 ± 2.85 | 4.50 ± 2.93 | < 0.01 |
Length of hospitalization (−x ± s) /d | 10.72 ± 3.47 | 8.81 ± 2.72 | < 0.01 |
Course before admission [M(P25–P75)]/d | 8 (6, 10) | 7 (5, 11) | 0.869 |
Allergic constitution [n (%)] | 40 (44.4) | 33 (21.2) | < 0.01 |
Signs and symptoms | |||
Fever [n (%)] | 86 (95.6) | 135 (81.8) | 0.002 |
Heat range (−x ± s) /d | 9.72 ± 3.80 | 5.00 ± 3.98 | < 0.01 |
Hot peak [M(P25–P75), °C] | 39.6 (39, 40) | 39 (38.5, 39.7) | < 0.01 |
Shortness of breath [n (%)] | 6 (6.7) | 8 (4.8) | 0.542 |
Breather [n (%)] | 7 (7.8) | 41 (24.8) | 0.01 |
Lung rales [n (%)] | 40 (44.4) | 68 (41.2) | 0.618 |
Lung wheezing [n (%)] | 6 (6.6) | 27 (16.3) | 0.27 |
Reduced breath sounds [n (%)] | 14 (15.6) | 21 (1.3) | 0.531 |
Laboratory characteristics | |||
WBC [M(P25–P75)]/ × 109 L−1 | 7.63 (5.97, 11.35) | 7.97 (6.12, 10.64) | 0.844 |
Neutrophil (−x ± s)/% | 67.34 ± 12.78 | 57.53 ± 15.20 | < 0.01 |
Eos [M(P25–P75)]/×109 L− 1 | 0.4 (0.045, 1.325) | 0.3 (0.07, 1.5) | 0.866 |
CRP [M(P25–P75)]/mg·L−1 | 25.72 (12.62, 51.23) | 7.58 (2.58, 18.23) | < 0.01 |
PLT [M(P25–P75)]/×109 L−1 | 275.5 (231.75, 356) | 321 (232, 394) | 0.109 |
LDH [M(P25–P75)]/U·L−1 | 545.9 (397.3, 655.5) | 389.3 (340.0, 389.3) | < 0.01 |
PA [M(P25–P75)]/mg·L−1 | 114 (92.75, 134) | 142 (115, 195.5) | < 0.01 |
DD [M(P25–P75)]/μg·L−1 | 1207 (484.5, 3677.75) | 367 (187, 367) | < 0.01 |
CK-MB [M(P25–P75)]/ng·mL−1 | 0.9 (0.5, 1.5) | 1.1 (0.6, 1.75) | 0.295 |
ALT [M(P25–P75)]/U·L−1 | 17.6 (12.55, 30.725) | 12.9 (10.1, 17.8) | < 0.01 |
AST [M(P25–P75)]/U·L−1 | 34.6 (27.425, 43.725) | 30.2 (24.95, 37.95) | 0.003 |
Serum MP-IgM | 3.46 (1.36, 5.49) | 3.2 (1.15, 5.14) | 0.154 |
Sputum MP-DNA copy number [n (%)] | |||
Low load group | 3 (3.3) | 20 (12.1) | 0.019 |
Medium load group | 13 (14.4) | 42 (25.5) | 0.041 |
High load group | 74 (82.2) | 103 (62.4) | 0.001 |
Humoral immunity | |||
IgG (−x ± s)/g·L−1 | 9.79 ± 2.86 | 9.43 ± 3.08 | 0.357 |
IgA [M(P25–P75)]/g·L−1 | 1.27 (0.96, 1.76) | 1.04 (0.6, 1.53) | 0.007 |
IgM [M(P25–P75)]/g·L−1 | 1.49 (1.09, 2.20) | 1.37 (0.95, 1.92) | 0.061 |
Cellular immunity [M(P25–P75), %] | |||
CD3+ | 66.96 (61.2, 73.05) | 65.5 (60.05, 72.15) | 0.634 |
CD3 + CD4+ | 34.14 (28.3, 40.32) | 34.2 (30.25, 39.2) | 0.524 |
CD3 + CD8+ | 27.25 (21.5, 27.25) | 25.8 (21.5, 30.2) | 0.24 |
CD4+/CD8+ | 1.30 (1.0, 1.3) | 1.3 (1.1, 1.7) | 0.117 |
CD3-CD (15 + 56) + | 10.35 (5.7, 15.7) | 10.2 (7.1, 14.8) | 0.715 |
CD3-CD19+ | 19.2 (14.02, 25.92) | 18.7 (12.95, 26.85) | 0.983 |
CD19 + CD23+ | 7.9 (5.4, 12.72) | 9.4 (6.55, 13.6) | 0.023 |
Radiological characteristics [n (%)] | |||
Lung consolidation | 84 (93.3) | 126 (76.36) | 0.001 |
Atelectasis | 9 (10) | 8 (4.8) | 0.123 |
Pleural effusion | 19 (21.1) | 18 (10.9) | 0.040 |
Pleural effusion site [n (%)] | |||
Left side | 9 (10) | 10 (6.1) | 0.331 |
Right side | 10 (11.1) | 11 (6.7) | 0.238 |
Treatment | |||
Medication time [M(P25–P75)]/Day n of course | |||
Azithromycin | 5.5 (4, 7) | 4 (3, 6) | 0.012 |
corticosteroids | 7 (5, 9) | 5 (3, 8) | 0.003 |
Fog time before tracheoscopy[M(P25–P75)]/d | 3 (2, 4) | 3 (2, 5) | 0.525 |