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Table 1 Baseline Characteristics

From: Immunogenicity and safety of a live herpes zoster vaccine in hematopoietic stem cell transplant recipients

 

HSCT 2–5 yr

(n = 26)

HSCT > 5 yr

(n = 15)

Chemotherapy

(n = 15)c

Healthy

(n = 30)

Median age, yr (IQR)

60 (55–63)

58 (53–62)

64 (57–69)

61 (57–66)

Male sex, n (%)

15 (58)

9 (60)

10 (67)

10 (33)

HSCT indication, n (%)

 Leukemia

11 (42)

4 (27)

14 (93)

N/A

 Lymphoma

2 (8)

7 (47)

  

 Multiple myeloma

6 (23)

1 (6.5)

  

 Myelodysplastic syndrome

4 (15)

2 (13)

  

 Othersa

3 (12)

1 (6.5)

1 (7)

 

Type of HSCT, n (%)

 Allogeneic

20 (77)

9 (60)

N/A

N/A

 Autologous

6 (23)

6 (40)

  

Time between HSCT or last chemo and the study date, mo (IQR)

35 (25–44)

87 (66–91)

65 (23–104)

N/A

Previous shingles history, yes, n (%)

12 (46)

9 (60)

6 (40)

0 (0)

Shingles within 2 yrs after HSCT or last chemo, n (%)

9/12 (75)

6/9 (67)

5/6 (83)

N/A

Median years from shingles to the study date (IQR)

3 (1.5–4)b

5 (5–7)

2.5 (1.3–6)

N/A

  1. IQR Interquartile range, yr Year, mo Month, N/A Not applicable, chemo Chemotherapy
  2. aAplastic anemia (n = 3), Myeloid sarcoma (n = 1), Granulocytic sarcoma (n = 1)
  3. b1 patient could not remember the exact time of shingles
  4. cAll but one patient had acute myeloid leukemia. None had received targeted monoclonal antibody therapies