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Table 3 Estimated clinical diagnostic parameters of the COVID-19 IB assays

From: IgG and IgM antibody formation to spike and nucleocapsid proteins in COVID-19 characterized by multiplex immunoblot assays

 

Estimated

95% Confidence Interval

Value

Lower Limit

Upper Limit

IgM antibodies only

 Sensitivity

0.7027

0.5283

0.8356

 Specificity

0.9913

0.9657

0.9985

 PPV

0.9286

0.7504

0.9875

 NPV

0.9542

0.9172

0.9757

IgG antibodies only

 Sensitivity

0.9189

0.7698

0.9788

 Specificity

0.9913

0.9657

0.9985

 PPV

0.9444

0.7999

0.9903

 NPV

0.9871

0.9596

0.9967

IgG and/or IgM antibodies

 Sensitivity

0.9723

0.8419

0.9986

 Specificity

0.9827

0.9533

0.9944

 PPV

0.9000

0.7540

0.9675

 NPV

0.9956

0.9720

0.9998

  1. PPV positive predictive vale; NPV negative predictive value
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BMC Infectious Diseases

ISSN: 1471-2334

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