Table 2 Antimicrobial susceptibility testing results of carbapenem-resistant Enterobacteriaceae (CRE)-colonizing strains
Antibiotics | All Strains (n = 219) | Non-infection group (n = 161) | Infection group (n = 58) | Klebsiella pneumonia (n = 133) | Escherichia coli (n = 54) | Other CRE (n = 32) | KPC (n = 69) | NDM (n = 77) | Other (n = 9) | NCP-CRE (n = 64) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% | R% | S% |
Cefepime | 96.8 | 1.4 | 96.3 | 1.2 | 98.3 | 1.7 | 96.2 | 1.5 | 98.2 | 0 | 96.9 | 3.1 | 100 | 0 | 100 | 0 | 100 | 0 | 89.1 | 4.7 |
Cefoxitin | 97.3 | 0.5 | 97.5 | 0 | 96.6 | 1.7 | 96.2 | 0 | 100 | 0 | 96.9 | 3.1 | 95.7 | 0 | 100 | 0 | 100 | 0 | 95.3 | 1.6 |
Ceftazidime | 97.7 | 1.4 | 97.5 | 1.2 | 98.3 | 1.7 | 97.7 | 0.8 | 98.2 | 1.9 | 96.9 | 3.1 | 100 | 0 | 100 | 0 | 100 | 0 | 92.2 | 4.7 |
Aztreonam | 81.3 | 16.4 | 78.9 | 18.0 | 87.9 | 12.1 | 91.0 | 7.5 | 66.7 | 31.5 | 65.6 | 28.1 | 100 | 0 | 58.4 | 37.7 | 55.6 | 22.2 | 92.2 | 7.8 |
Ertapenem | 99.5 | 0.5 | 100 | 0 | 98.3 | 1.7 | 100 | 0 | 100 | 0 | 96.9 | 3.1 | 100 | 0 | 100 | 0 | 100 | 0 | 98.4 | 1.6 |
Imipenem | 74.4 | 16.4 | 69.6 | 19.3 | 87.9 | 8.6 | 72.2 | 17.3 | 72.2 | 22.2 | 87.5 | 3.1 | 100 | 0 | 100 | 0 | 66.7 | 11.1 | 17.2 | 54.7 |
Meropenem | 85.4 | 7.3 | 83.2 | 9.3 | 91.4 | 1.7 | 85.0 | 4.5 | 81.5 | 14.8 | 93.8 | 6.3 | 100 | 0 | 100 | 0 | 100 | 0 | 50.0 | 25.0 |
Gentamicin | 67.6 | 32.0 | 61.5 | 37.9 | 84.5 | 15.5 | 78.2 | 21.1 | 40.7 | 59.3 | 68.8 | 31.3 | 92.8 | 7.2 | 51.9 | 46.8 | 55.6 | 44.4 | 60.9 | 39.1 |
Amikacin | 37.9 | 60.7 | 26.7 | 71.4 | 69.0 | 31.0 | 54.1 | 45.1 | 11.1 | 87.0 | 15.6 | 81.3 | 85.5 | 14.5 | 13.0 | 87.0 | 22.2 | 77.8 | 18.8 | 76.6 |
Minocycline | 42.5 | 44.8 | 46.6 | 42.9 | 31.0 | 50.0 | 45.9 | 41.4 | 35.2 | 55.6 | 40.6 | 40.6 | 23.2 | 60.9 | 40.3 | 48.1 | 0 | 88.9 | 71.9 | 17.2 |
Ciprofloxacin | 86.3 | 11.0 | 84.5 | 12.4 | 91.4 | 6.9 | 90.2 | 7.5 | 87.0 | 9.3 | 68.8 | 28.1 | 100 | 0 | 75.3 | 20.8 | 55.6 | 22.2 | 89.1 | 9.4 |
Fosfomycin | 57.1 | 32.4 | 46.6 | 41.6 | 86.2 | 6.9 | 78.2 | 11.3 | 22.2 | 74.1 | 28.1 | 50.0 | 100 | 0 | 18.2 | 63.6 | 33.3 | 66.7 | 60.9 | 25.0 |
Piperacillin-tazobactam | 95.4 | 3.2 | 95.0 | 3.7 | 96.6 | 1.7 | 94.7 | 3.0 | 98.2 | 1.9 | 93.8 | 6.3 | 100 | 0 | 100 | 0 | 88.9 | 11.1 | 85.9 | 9.4 |
Trimethoprim-sulfamethoxazole | 73.1 | 26.9 | 80.8 | 19.3 | 51.7 | 48.3 | 68.4 | 31.6 | 77.8 | 22.2 | 84.4 | 15.6 | 47.8 | 52.2 | 84.4 | 15.6 | 44.4 | 55.6 | 90.6 | 9.4 |
Colistin | 7.8 | 92.2 | 9.9 | 90.1 | 1.7 | 98.3 | 6.0 | 94.0 | 3.7 | 96.3 | 21.9 | 78.1 | 2.9 | 97.1 | 10.4 | 89.6 | 0 | 100 | 9.4 | 90.6 |
Tigecycline | 16.9 | 83.1 | 20.5 | 79.5 | 6.9 | 93.1 | 26.3 | 73.7 | 0 | 100 | 6.3 | 93.8 | 7.2 | 92.8 | 10.4 | 89.6 | 0 | 100 | 37.5 | 62.5 |