Fig. 1

Streptococcus pneumoniae isolate MICs (μg/ml) in relationship between penicillin and oral beta-lactams, amoxicillin and cefdinir. a and b) The correlation between penicillin and oral beta-lactam MICs are represented by amoxicillin and cefdinir. MIC distribution was highlighted to represent CLSI classification of susceptible, intermediate, and resistant MICs using the penicillin non-meningitis breakpoint and respective oral beta-lactam breakpoints. The red box highlights the number of isolates and region for error misclassification. c) Use of penicillin MIC ≤0.06 μg/ml to predict cefdinir susceptibility. The red box highlights the discrepancy of the number of isolates that would have been unable to be classified as cefdinir susceptible. a) Penicillin and Amoxicillin (249 isolates). b) Penicillin and Cefdinir (249 isolates). c) Penicillin and Cefdinir with CLSI Guidance (249 isolates)