From: Serum surfactant protein D in COVID-19 is elevated and correlated with disease severity
 | Overall | Mild | Severe | P-value |
---|---|---|---|---|
Gender(M/F), n/n | 20/19 | 16/14 | 4/5 | 0.720 |
Age (years)a | 49 (31–56) | 49 (25–55) | 54 (47–75) | 0.030 |
Current Smokers, n (%) | 4 (10) | 2 (7) | 2 (22) | 0.223 |
Diabetes History, n (%) | 4 (10) | 2 (7) | 2 (22) | 0.223 |
CVD History, n (%) | 3 (8) | 1 (3) | 2 (22) | 0.127 |
WBC(×109/L)a | 6.27 (4.64–7.82) | 5.70 (4.34–7.66) | 6.42 (5.47–8.98) | 0.243 |
Lymphcytes(×109/L)a | 1.16 (0.84–1.68) | 1.31 (1.02–1.78) | 1.04 (0.59–1.16) | 0.049 |
CRP (mg/L)a | 3.50 (0.50–16.50) | 0.59 (0.50–5.06) | 38.9 (17.3–66.6) | 0.000 |
ESR (mm/h)a | 22.0 (12.0–39.5) | 20.2 (10.6–29.4) | 41.7 (27.0–76.8) | 0.004 |
IL-6(pg/mL)a | 21.6 (12.0–30.8) | 11.19 (7.45–15.54) | 18.71 (17.20–32.52) | 0.002 |
D-dimer (mg/L)a | 0.43 (0.19–0.88) | 0.35 (0.15–0.52) | 4.49 (1.29–7.00) | 0.000 |
Lactic Acid (mmol/L)a | 0.88 (0.68–1.54) | 0.80 (0.68–1.17) | 1.95 (1.15–2.25) | 0.004 |
SP-D (ng/mL) | 292.9 ± 130.7 | 245.9 ± 90.0 | 449.7 ± 125.8 | 0.000 |
CT imaging scorea | 9.0 (5.0–11.0) | 9.0 (5.0–9.5) | 10.0 (9.0–15.0) | 0.011 |
Length of stay (days) | 12.0 ± 4.3 | 10.6 ± 3.5 | 16.6 ± 3.5 | 0.000 |
DNA-N (days)a | 10.0 (6.0–14.0) | 8.5 (5.0–11.8) | 14.0 (11.0–17.0) | 0.004 |