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Table 3 Cohort characteristics stratified by mortality outcomes

From: Association between oral antimalarial medication administration and mortality among patients with Ebola virus disease: a multisite cohort study

 

Survived (n = 180, %)

Died (n = 244, %)

p-value

Age (years)*

28.7 ± 15.3

31.8 ± 20.8

0.080

Sex

 Female

108 (60.0)

145 (59.4)

0.921

 Male

72 (40.0)

99 (40.6)

Length of Stay (days)†

13, (10, 17)

4, (3, 6)

0.000

Country of Treatment

 Sierra Leone

119 (66.1)

171 (70.1)

0.399

 Liberia

61 (33.9)

73 (29.9)

Rapid diagnostic test for malaria results

 Positive

17 (9.4)

31 (12.7)

0.082

 Negative

94 (52.2)

101 (41.4)

 Not Tested

69 (38.3)

112 (45.9)

Cycle Threshold Value /Viral Load

 ≥22 (Low Viral Load)

81 (45.0)

41 (16.8)

0.000

  < 22 (High Viral Load)

50 (27.8)

109 (44.7)

 Missing

49 (27.2)

94 (38.5)

Treatments received first 48 hours of care

 Artemether-lumefantrine

169 (93.9)

207 (84.8)

0.005

 ORS

166 (92.2)

207 (84.8)

0.023

 Cefixime

163 (90.6)

197 (80.7)

0.006

 Multivitamins

121 (67.2)

140 (57.4)

0.044

 Ondansetron

48 (26.7)

63 (25.8)

0.911

 Vitamin C

164 (92.8)

219 (89.8)

0.740

 Zinc Sulphate

7 (3.9)

15 (6.1)

0.378

 Vitamin A

152 (84.4)

178 (73.0)

0.006

Signs & symptoms first 48 hours of care

 Abnormal Bleeding

42 (23.3)

80 (32.8)

0.039

 Coma

0 (0.0)

6 (2.5)

0.041

 Diarrhea

111 (61.7)

187 (76.6)

0.001

 Dysphagia

60 (33.3)

111 (45.5)

0.012

 Dyspnea

41 (22.8)

94 (38.5)

0.001

 Jaundice

2 (1.1)

23 (9.4)

0.000

 Anorexia

116 (64.4)

167 (68.4)

0.405

 Abdominal Pain

108 (60.0)

157 (64.3)

0.363

 Vomiting

104 (57.8)

150 (61.5)

0.483

  1. *Values represent mean with standard deviation
  2. † Values represent median with interquartile range