parameters | AUC (95% CI) | cutoff value | SEN | SPE | PPV | NPV | LR+ | LR- |
---|---|---|---|---|---|---|---|---|
For all patients | ||||||||
Age (years) | 0.674 (0.623, 0.723) | > 66 | 74.2 | 52.9 | 26.5 | 90 | 1.58 | 0.49 |
α-HBDH (U/L) | 0.829 (0.784,0.867) | > 674.49 | 65.6 | 88.8 | 56.3 | 92.1 | 5.84 | 0.39 |
AST/ALT ratio | 0.842 (0.800, 0.879) | > 2.26 | 87.9 | 65.1 | 36.5 | 95.9 | 2.51 | 0.19 |
mAST/ALT ratio | 0.803 (0.757, 0.843) | > 0.659 | 69.2 | 80.6 | 44.6 | 92.1 | 3.57 | 0.38 |
cAST/ALT ratio | 0.847 (0.805, 0.883) | > 1.728 | 86.2 | 69.2 | 38.6 | 95.7 | 2.8 | 0.2 |
M1 | 0.888 (0.851, 0.919) | > 10.21 | 78.8 | 83.4 | 52.0 | 94.5 | 4.74 | 0.25 |
sM1 | 0.889 (0.852, 0.920) | > 11.36 | 83.3 | 79.6 | 48.2 | 95.4 | 4.08 | 0.21 |
M2 | 0.878 (0.840, 0.910 ) | > 9.604 | 83.3 | 81.3 | 50.5 | 95.5 | 4.46 | 0.20 |
sM2 | 0.877 (0.838, 0.909) | > 10.279 | 86.4 | 77.2 | 46.3 | 96.1 | 3.78 | 0.18 |
M3 | 0.880 (0.841, 0.912) | > 9.958 | 86.4 | 76.1 | 45.2 | 96.1 | 3.62 | 0.18 |
sM3 | 0.880 (0.842, 0.912) | > 10.562 | 84.9 | 76.5 | 45.2 | 95.7 | 3.61 | 0.20 |
For ICU patients | ||||||||
AST/ALT ratio | 0.731 (0.618, 0.826) | > 3.3 | 63.6 | 77.3 | 67.7 | 73.9 | 2.8 | 0.47 |
mAST/ALT ratio | 0.743 (0.631, 0.836) | > 0.553 | 90.9 | 47.7 | 56.6 | 87.5 | 1.74 | 0.19 |
cAST/ALT ratio | 0.723 (0.609, 0.819) | > 2.50 | 63.4 | 77.3 | 67.7 | 73.9 | 2.8 | 0.47 |