Table 4 Cumulative fraction of response (CFR) for achieving PK/PD index with different antimicrobials against Neisseria gonorrhoeae in Nanjing, China from 2013 to 2020
Antibiotic | Single Dose Regimen | CFR(%) | ||
|---|---|---|---|---|
2013–2016 | 2017–2020 | |||
Ceftriaxone | 250 mg im | 99.75 | 96.45 | |
500 mg im | 99.99 | 97.07 | ||
1000 mg im | 100 | 98.19 | ||
2000 mg iv | 100 | 98.81 | ||
Cefixime | 400 mg po | 98.35 | 93.79 | |
800 mg po | 100 | 97.93 | ||
Azithromycin | 1000 mg po | 24.88 | 19.52 | |
2000 mg po | 43.51 | 55.33 | ||
Penicillin | 4,800,000U im | 5.4 | 3.35 | |
Tetracycline | 500 mg po | 10.03 | 13.61 | |
Ciprofloxacin | 500 mg po | 0 | 0 | |
Zoliflodacin | 2000 mg po | 100 | 100 | |
3000 mg po | 100 | 100 | ||