Table 3 Quality of life of included participants
|  | Baseline (n = 456) | 1st year (n = 335) | 2nd year (n = 331) | 3nd year (n = 302) | 4th year (n = 253) | 5th year (n = 209) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Moderate | Severe | Moderate | Severe | Moderate | Severe | Moderate | Severe | Moderate | Severe | Moderate | Severe | |
EQ-5D | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 MO, n (%) | 31(6.8) | 2(0.4) | 19(5.7) | 0(0) | 17(5.1) | 1(0.3) | 17(5.6) | 1(0.3) | 17(6.7) | 0(0) | 16(7.7) | 0(0) |
 SC, n (%) | 5(1.1) | 1(0.2) | 4(1.2) | 0(0) | 4(1.2) | 0(0) | 3(1.0) | 0(0) | 1(0.4) | 0(0) | 1(0.5) | 0(0) |
 UA, n (%) | 19(4.2) | 3(0.6) | 18(5.4) | 0(0) | 14(4.2) | 1(0.3) | 11(3.6) | 0(0) | 13(5.1) | 0(0) | 11(5.3) | 0(0) |
 PD, n (%) | 96(21.1) | 5(1.1) | 57(17.0) | 3(0.9) | 56(16.9) | 3(0.9) | 56(18.5) | 1(0.3) | 36(14.2) | 1(0.4) | 27(12.9) | 1(0.5) |
 AD, n (%) | 96(21.1) | 2(0.4) | 42(12.5) | 1(0.3) | 38(11.5) | 3(0.9) | 31(10.3) | 1(0.3) | 23(9.1) | 0(0) | 18(8.6) | 1(0.5) |
EQ-5D index, mean ± SD | 0.916 ± 0.208 | 0.938 ± 0.177 | 0.936 ± 0.199 | 0.943 ± 0.153 | 0.956 ± 0.125 | 0.949 ± 0.159 | ||||||
EQ-5D VAS, mean ± SD | 80.6 ± 13.0 | 82.1 ± 12.2 | 83.4 ± 12.7 | 85.9 ± 12.6 | 85.8 ± 13.1 | 86.9 ± 12.1 | ||||||