Table 2 Basic characteristics of included studies
From: Urokinase in the treatment of tuberculous pleurisy: a systematic review and meta-analysis
Author | Experimental Group | Control Group | Male/Female Ratio | Age (years) | Anti-tuberculosis | UK Dose | Drainage Method | Outcomes | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Experimental Group | Control Group | Experimental Group | Control Group | Treatment | (10,000U) | Experimental Group | Control Group | Â |
Ren HW [4] | 205 | 205 | 129/76 | 118/87 | 16～76 | 16～74 | 3HRZE/6HR | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.3.5 |
Zhang XY [5] | 30 | 30 | 18/12 | 19/11 | 27～80 | 29～75 | HRZE | 10 | Puncture and Catheter Drainage | Thoracentesis | 1.3 |
Luo LQ [10] | 43 | 43 | 28/15 | 25/17 | 22～58 | 25～60 | 2HRZE/10HRE | 20 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.4.5 |
Wang G [11] | 57 | 55 | 69/43 (There was no distinction between experimental and control groups) | 15～59 (There was no distinction between experimental and control groups) | HRZE | 10 | Central venous catheter drainage | Puncture and Catheter Drainage | 3 | ||
Zhang XW [12] | 18 | 18 | 9/9 | 10/8 | 46～77 | 45～78 |  | 10 | Central venous catheter drainage | Thoracentesis | 1.2 |
Chen YC [13] | 30 | 30 | 15/15 | 16/14 | 36.4 ± 12.7 | 35.5 ± 13.2 | 2HRZE/4HR | 10 | Central venous catheter drainage | Central venous catheter drainage | 1.2.3.5 |
Li YY [14] | 50 | 50 | 31/19 | 32/18 | 21～64 | 21～64 | 2HRZE/10HRE | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.2.3 |
Zhou GS [15] | 59 | 55 | 31/28 | 29/26 | 23～76 | 21～79 | 2HRZ/4HR | 20 | Puncture and Catheter Drainage | Thoracentesis | 1.2.3.4.5 |
Du L [16] | 20 | 20 | 23/17 (There was no distinction between experimental and control groups ) | 17-57(There was no distinction between experimental and control groups) |  | 3～5 | Thoracentesis | Thoracentesis | 1.2 | ||
Liu HD [17] | 30 | 30 | 18/12 | 17/13 | 18～74 | 19～72 | 2HRZE/6HRE | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.2.3 |
Cao, G.Q.; Li, L.; Wang, Y.B. [18] | 86 | 85 |  |  |  |  |  | 2～6 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 4 |
Wang CM [19] | 50 | 50 | 32/18 | 30/20 | 17～65 | 16～62 |  | 10 | Puncture and Catheter Drainage | Thoracentesis | 2.3 |
Liu JC [20] | 88 | 88 | 47/41 | 46/42 | 24～56 | 23～54 | HRZE | 10 | Puncture and Catheter Drainage | Thoracentesis | 1.2 |
Hu ZF [21] | 42 | 42 | 62/22 (There was no distinction between experimental and control groups) | 18～68 (There was no distinction between experimental and control groups) |  | 10 | Thoracentesis | Thoracentesis | 1 | ||
Jiang B [22] | 20 | 20 | There was no significant difference in age, sex, course of disease and pulmonary function between the two groups (P > 0.05) |  | 10 | Thoracentesis | Thoracentesis | 2.3 | |||
Li Y [23] | 30 | 30 | 42/18 (There was no distinction between experimental and control groups) | 18～65 (There was no distinction between experimental and control groups) | 2HRZ/4HR | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.2.3 | ||
Shi YH [24] | 130 | 130 | 62/68 | 74/56 | 17～85 | 16～70 |  | 10 | Thoracentesis | Thoracentesis | 1.2 |
Wei J [25] | 40 | 40 | 24/16 | 22/18 | 18～53 | 17～55 | 3HRZ/6HR | 10 | Central venous catheter drainage | Thoracentesis | 2.3 |
Wang MZ [26] | 40 | 40 | 28/12 | 27/13 | 36.7±20.5 | 35.6 ± 19.7 | 2HRZE/4HR | 10 | Central venous catheter drainage | Thoracentesis | 1.2 |
Yuan X [27] | 36 | 36 | 26/10 | 24/12 | 18～56 | 17～59 |  | 10 | Puncture and Catheter Drainage | Thoracentesis | 1.2.3 |
Yuan X [28] | 139 | 139 | 72/67 | 70/69 | 17～85 | 16～70 |  | 10 | Puncture and Catheter Drainage | Thoracentesis | 1.2 |
Zheng FD [29] | 30 | 30 | 28/32 (There was no distinction between experimental and control groups) | 16～62 (There was no distinction between experimental and control groups) | 2SHRZ/4HR | 20 | Central venous catheter drainage | Thoracentesis | 2.3 | ||
Li CH [30] | 40 | 36 | 28/12 | 27/9 | 32.3 ± 7.2 | 35.8 ± 6.3 | 2HRZE/6HR | 10 | Central venous catheter drainage | Central venous catheter drainage | 1.3 |
Cases, V.E.; Lorenzo, D.M.; Gonzdlez-Mlina, A [31] | 12 | 17 | 21/8 (There was no distinction between experimental and control groups) | Â | Â | Â | 12.5 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.3 | |
Kwak, S. M.; Park, C.S.; Cho, J.H [32] | 21 | 22 | 15/6 | 12/10 | 30.6 ± 7.8 | 29.9 ± 10.0 | 2HRZE/4HRE | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.3 |
Zhao RZ [33] | 34 | 35 | 23/11 | 22/13 | 16～51 | 19～57 | 2HRS/4HR | 10 | Thoracentesis | Thoracentesis | 2.3 |
Yao ZY [34] | 19 | 13 | There was no significant difference in sex, age, course of disease, ESR and volume of pleural fluid before injection between the two groups (P > 0.05) | 2HRZS/6HR | 10 | Puncture and Catheter Drainage | Puncture and Catheter Drainage | 1.4.5 | |||
Huang YM [35] | 20 | 20 | 9/11 | 11/9 | 41.8 ± 9.0 | 37.6 ± 10.6 | 2HRS/4HR | 25 | Central venous catheter drainage | Central venous catheter drainage | 1.2.3 |
Ding D [36] | 42 | 39 | 23/19 | 25/14 | 15～55 | 13～50 | 2HRS/4HR | 10 | Thoracentesis | Thoracentesis | 1.3 |