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Table 4 Subgroup analyses of the association between main clinic outcomes and monotherapy stratified by outcome predictors

From: Clinical success of anti-infective combination therapy compare to monotherapy in patients with carbapenem-resistant Pseudomonas aeruginosa infection: a 10-years retrospective study

 

Adjusted OR (95% CI)

p value

Adjusted OR (95% CI)

p value

 

Male(n=180)

 

Female(n=99)

 

Clinical success

0.441(0.215-0.904)

0.025

0.840(0.327-2.161)

0.717

Complete clinical success

1.219(0.615-2.415)

0.571

0.599(0.233-1.540)

0.287

28-day mortality

1.000(0.422-2.371)

1.000

0.557(0.30-2.383)

0.430

 

SOFA < 2(n=96)

 

SOFA ≥ 2(n=183)

 

Clinical success

0.599(0.190-1.893)

0.383

0.469(0.231-0.953)

0.036

Complete clinical success

1.065(0.429-2.642)

0.891

0.697(0.332-1.463)

0.340

28-day mortality

0.777(0.191-3.163)

0.724

0.906(0.376-2.185)

0.826

 

Charlson Comorbidity Score < 6(n=118)

 

Charlson Comorbidity Score ≥ 6(n=161)

 

Clinical success

0.626(0.250-1.565)

0.316

0.467(0.222-0.980)

0.044

Complete clinical success

0.715(0.309-1.656)

0.434

1.037(0.502-2.142)

0.922

28-day mortality

2.089(0.596-7.322)

0.250

0.546(0.208-1.433)

0.219