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Table 4 Validity indices of symptoms and single-site infection of gonorrhoea and chlamydia at each specific anatomical site, Brazil, 2023

From: Patterns of Chlamydia trachomatis and Neisseria gonorrhoeae in different anatomical sites among Pre-Exposure Prophylaxis (PrEP) users in Brazil

 

Chlamydia trachomatis

Neisseria gonorrhoeae

95% CI*

P-value

95% CI*

P-value

Symptoms when tested

Positive predict value

0.154 (0.027–0.404)

0.124

0.154 (0.027–0.404)

0.124

Negative predict value

0.886 (0.830–0.929)

< 0.001

0.937 (0.892–0.968)

< 0.001

Sensitivity

0.100 (0.017–0.278)

0.136

0.167 (0.030–0.431)

0.121

Specificity

0.927 (0.878–0.961)

< 0.001

0.931 (0.884–0.963)

< 0.001

Urine samples

Positive predict value

0.857 (0.506–0.991)

< 0.001

0.800 (0.372–0.987)

< 0.001

Negative predict value

0.905 (0.854–0.943)

< 0.001

0.941 (0.899–0.970)

< 0.001

Sensitivity

0.273 (0.119–0.477)

0.004

0.286 (0.099–0.545)

0.018

Specificity

0.993 (0.972–1.000)

< 0.001

0.994 (0.973–1.000)

< 0.001

Anal samples

Positive predict value

0.947 (0.788–0.997)

< 0.001

0.923 (0.703–0.995)

< 0.001

Negative predict value

0.974 (0.941–0.992)

< 0.001

0.988 (0.962–0.988)

< 0.001

Sensitivity

0.818 (0.627–0.940)

< 0.001

0.857 (0.621–0.975)

< 0.001

Specificity

0.993 (0.972–1.000)

< 0.001

0.994 (0.973–1.000)

< 0.001

  1. *CI: Confidence Interval; P-value refers to χ2 test