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Table 1 Demographic and clinical characteristics of the study participants

From: The impact of preoperative biliary drainage on postoperative healthcare-associated infections and clinical outcomes following pancreaticoduodenectomy: a ten-year retrospective analysis

Characteristics

Total participants

(N = 2842)

PBD group

Non-PBD group

P value

Infection

Non-infection

P value

(n = 877)

(n = 1965)

(n = 247)

(n = 2595)

Age, years, mean ± SD

58.1 ± 11.5

60.0 ± 10.2

57.2 ± 12.0

< 0.001

58.6 ± 11.1

58.0 ± 11.6

0.47

Age, years, n (%)

 < 65

1963(69.1)

567(64.7)

1396(71.0)

0.001

168(8.6)

1795(91.4)

0.707

 ≥65

879(30.9)

310(35.3)

569(29.0)

 

79(9)

800(91)

 

Gender, n (%)

 Male

1738(61.2)

574(65.5)

1164(59.2)

0.002

158(9.1)

1580(90.9)

0.342

 Female

1104(38.8)

303(34.5)

801(40.8)

 

89(8.1)

1015(91.9)

 

BMI, Kg/m2, mean ± SD

23.4 ± 3.3

23 ± 3.2

23.5 ± 3.3

< 0.001

24.3 ± 3.4

23.3 ± 3.3

< 0.001

BMI, Kg/m2, n (%)

 < 18.5

167(5.9)

66(7.5)

101(5.1)

0.001

7(4.2)

160(95.8)

0.004

 18.5–24

1513(53.2)

495(56.4)

1018(51.8)

 

117(7.7)

1396(92.3)

 

 24–27

772(27.2)

218(24.9)

554(28.2)

 

75(9.7)

697(90.3)

 

 ≥27

390(13.7)

98(11.2)

292(14.9)

 

48(12.3)

342(87.7)

 

Smoking, n (%)

843(29.7)

268(30.6)

575(29.3)

0.485

72(8.5)

771(91.5)

0.854

Drinking, n (%)

827(29.1)

269(30.7)

558(28.4)

0.217

81(9.8)

746(90.2)

0.181

Hypertension, n (%)

719(25.3)

215(24.5)

504(25.6)

0.521

72(10)

647(90)

0.145

Diabetes, n (%)

542(19.1)

166(18.9)

376(19.1)

0.897

43(7.9)

499(92.1)

0.487

Coronary disease, n (%)

244(8.6)

71(8.1)

173(8.8)

0.534

23(9.4)

221(90.6)

0.67

Primary disease, n (%)

 Pancreatic cancer

831(29.2)

253(28.8)

578(29.4)

< 0.001

55(6.6)

776(93.4)

0.001

 Cholangiocarcinoma

640(22.5)

329(37.5)

311(15.8)

 

76(11.9)

564(88.1)

 

 Duodenal carcinoma

438(15.4)

112(12.8)

326(16.6)

 

44(10)

394(90)

 

 Ampullary carcinoma

217(7.6)

116(13.2)

101(5.1)

 

23(10.6)

194(89.4)

 

 Intraductal papillary mucinous neoplasm (IPMN)

176(6.2)

11(1.3)

165(8.4)

 

6(3.4)

170(96.6)

 

 Others

540(19.0)

56(6.4)

484(24.6)

 

43(8)

497(92)

 

Operation approach, n (%)

 Open

2013(70.8)

638(72.7)

1375(70)

0.007

194(9.6)

1819(90.4)

0.019

 Robot

619(21.8)

161(18.4)

458(23.3)

 

36(5.8)

583(94.2)

 

 Laparoscope

163(5.7)

63(7.2)

100(5.1)

 

15(9.2)

148(90.8)

 

 Robot+laparoscope

47(1.7)

15(1.7)

32(1.6)

 

2(4.3)

45(95.7)

 
  1. PBD preoperative biliary drainage, BMI Body Mass Index