Association of haemato-biochemical indices and blood composite ratios with microfilaridermia in Onchocerciasis patients

Table 3 Biochemical and Haematological Variabilities among Study Participants

Variable	unit	N	a-Microfilaridermic (n = 34)	N	Microfilaridermic (n = 105)	p-value
Variable	unit	N	median (IQR)	N	median (IQR)	p-value
RBC	x10⁹/L	34	4.73 [4.24–5.24]	105	4.57 [4.20–4.95]	0.209
HGB	g/dL	34	13.5 [12.1–14.6]	105	13.1 [12.1–14.2]	0.390
HCT	%	34	41.2 [38.2–43.6]	105	40.1 [37.1–42.8]	0.253
PLT	x10⁹/L	34	196 [123–246]	105	200 [161–247]	0.343
Total WBC	x10⁹/L	34	4.71 [3.97–5.50]	105	5.39 [4.78–6.60]	0.001
Neutrophil Abs	x10⁹/L	34	1.78 [1.54–2.54]	105	1.99 [1.46–2.69]	0.602
Lymphocyte Abs	x10⁹/L	34	2.07 [1.79–2.44]	105	2.28 [1.85–2.85]	0.069
Monocyte Abs	x10⁹/L	34	0.43 [0.32–0.53]	105	0.47 [0.35–0.59]	0.110
Eosinophil Abs	x10⁹/L	34	0.14 [0.08–0.36]	105	0.42 [0.19–0.84]	< 0.0001
Basophil Abs	x10⁹/L	34	0.02 [0.01–0.03]	105	0.03 [0.02–0.04]	0.001
Neutrophil %	%	34	40.4 [35.6–48.4]	105	37 [31.2–44.7]	0.055
Lymphocyte %	%	34	44.9 [38.9–53.6]	105	42.2 [36.3–49.0]	0.198
Monocyte %	%	34	9.0 [7.7–9.8]	105	8.0 [6.5–10.5]	0.216
Eosinophil %	%	34	3.2 [1.9–7.5]	105	8.0 [3.8–14.1]	< 0.0001
Basophil %	%	34	0.4 [0.3–0.6]	105	0.5 [0.4–0.7]	0.057
ALT	U/L	34	24.0 [20.1–29.6]	105	22.4 [17.5–30.2]	0.513
AST	U/L	34	22.3 [18.5–29.0]	105	23.0 [17.8–28.5]	0.745
GGT	U/L	34	33.4 [21.9–39.6]	105	25.3 [20.1–32.8]	0.013
Creatinine	µmol/L	34	95.0 [79.0–103.0]	105	91.0 [79.5–101.0]	0.289
eGFR	mL/min/1.73m²	34	89.7 [82.8–94.8]	105	94.8 [84.4–107.5]	0.040

RBC = red blood cell; HGB = haemoglobin concentration; HCT = haematocrit; PLT = platelet; WBC = white blood cell; abs = absolute; ALT = alanine transaminase; AST = aspartate transaminase; GGT = gamma-glutamyl transferase; eGFR = estimated glomerular filtration; IQR = inter-quartile range. Mann-Whitney U-test was used for all analyses. p-value < 0.05 was considered statistically significant

ISSN: 1471-2334