Fig. 2

The diagnostic value of LDNs and MDSC subsets in sepsis. LDNs, MDSC subsets, CRP, and PCT levels in patients with healthy controls, infection, and sepsis (a). ROC curves for biomarkers to diagnose and distinguish between sepsis and infection (b). Forest plot showing the results of ordinal logistic regression analysis (c). OR and CIs significantly associated with sepsis were shown in red when OR > 1 and in blue when OR < 1. Abbreviations: ROC, receiver operator characteristics; OR, odds ratio; CI, confidence interval; LDNs, low-density neutrophils; MDSCs, myeloid-derived suppressor cells; M-MDSCs, monocytic MDSCs; PMN-MDSCs, polymorphonuclear MDSCs; CRP, C-reactive protein; PCT, procalcitonin