Fig. 6

The prognostic value of LDNs and MDSC subsets in the sepsis group. Comparison of LDNs, MDSC subsets, CRP， and PCT between 28-day hospital survivors and non-survivors (a). The ROC curve of M-MDSCs for predicting 28-day mortality (b). A Kaplan–Meier survival curve was drawn to show the 28-day survival rate for sepsis patients (c). Univariate Cox proportional hazards regression analysis of prognostic factors in sepsis patients (d). HR and CIs significantly associated with sepsis were shown in red when HR > 1 and in blue when HR < 1. Abbreviations: LDNs, low-density neutrophils; MDSCs, myeloid-derived suppressor cells; M-MDSCs, monocytic MDSCs; PMN-MDSCs, polymorphonuclear MDSCs; CRP, C-reactive protein; PCT, procalcitonin; AUC, area under the curve; HR, hazard ratio; CI, confidence interval