Table 1 Baseline characteristics of patients

Demographics and clinical characteristics

Male, n (%)

16 (50.0)

18 (54.5)

36 (69.2)

0.167

0.170

Age (year)

60.00 (53.25–65.50)

63.00 (34.00–73.50)

66.50 (53.00–74.75)

0.076

0.176

Hypertension, n (%)

0 (0.0)

9 (27.3)

24 (46.2)

< 0.001

0.082

Diabetes, n (%)

0 (0.0)

11 (33.3)

20 (38.5)

< 0.001

0.632

Organ dysfunction, n (%)

Respiratory

0 (0.0)

0 (0.0)

28 (53.8)

< 0.001

< 0.001

Cardiovascular

0 (0.0)

5 (15.2)

40 (76.9)

< 0.001

< 0.001

Hepatic

0 (0.0)

3 (9.4)

30 (57.7)

< 0.001

< 0.001

Hematologic

0 (0.0)

0 (0.00)

25 (48.1)

< 0.001

< 0.001

Neurologic

0 (0.0)

0 (0.00)

28 (53.8)

< 0.001

< 0.001

Renal

0 (0.0)

0 (0.00)

18 (34.6)

< 0.001

0.006

Severity of infection

Number of dysfunctional organs

0 (0–0)

0 (0–0.5)

3.00 (1.25–5.00)

< 0.001

< 0.001

SOFA score

0 (0–0)

0 (0–0.5)

7 (3–12)

< 0.001

< 0.001

Laboratory examinations

Leukocyte count (×10⁹/L)

5.26 (4.34–6.70)

7.66 (5.59–10.48)

11.02 (7.12–15.82)

< 0.001

0.005

Lymphocyte count (×10⁹/L)

1.72 (1.38–2.08)

1.35 (0.90–1.97)

0.76 (0.45–1.26)

< 0.001

< 0.001

Monocyte count (×10⁹/L)

0.35 (0.24–0.40)

0.50 (0.35–0.72)

0.50 (0.27–0.83)

< 0.001

0.917

Neutrophil count (×10⁹/L)

2.92 (2.31–4.30)

5.42 (3.35–8.05)

9.63 (5.67–14.23)

< 0.001

< 0.001

Lymphocyte percentage (%)

32.10 (26.45–38.49)

16.50 (12.80–28.20)

6.55 (3.95–10.88)

< 0.001

< 0.001

Monocyte percentage (%)

5.60 (4.95–7.48)

7.00 (4.65–8.75)

4.35 (2.33–6.83)

0.003

0.003

Neutrophil percentage (%)

59.35 (53.48–64.45)

73.00 (60.45–78.00)

88.15 (79.20–91.58)

< 0.001

< 0.001

MLR

0.189 (0.148–0.235)

0.390 (0.228–0.664)

0.598 (0.306–0.984)

< 0.001

0.025

NLR

1.853 (1.410–2.437)

4.361 (2.190–6.357)

13.03 (7.660–23.35)

< 0.001

< 0.001