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  1. The rapid identification of acid-fast bacilli recovered from patient specimens as Mycobacterium tuberculosis complex (MTC) is critically important for accurate diagnosis and treatment. A thin-layer immunochromato...

    Authors: Kinuyo Chikamatsu, Akio Aono, Hiroyuki Yamada, Tetsuhiro Sugamoto, Tomoko Kato, Yuko Kazumi, Kiyoko Tamai, Hideji Yanagisawa and Satoshi Mitarai
    Citation: BMC Infectious Diseases 2014 14:54
    Content type: Research article Published on:

  2. The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacteri...

    Authors: Sebabrata Mahapatra, Ann M Hess, John L Johnson, Kathleen D Eisenach, Mary A DeGroote, Phineas Gitta, Moses L Joloba, Gilla Kaplan, Gerhard Walzl, W Henry Boom and John T Belisle
    Citation: BMC Infectious Diseases 2014 14:53
    Content type: Research article Published on:

  3. Mycobacterium tuberculosis infection can activate the immune system, leading to characteristic pathological changes such as inflammatory granuloma, caseous necrosis, and cavity formation.

    Authors: Chong Wang, Yan-Yuan Li, Xiang Li, Li-Liang Wei, Xiu-Yun Yang, Dan-Dan Xu, Ting-Ting Jiang, Zhong-Jie Li, Zhong-Liang Chen, Xing Zhang, Ji-Yan Liu, Ze-Peng Ping and Ji-Cheng Li
    Citation: BMC Infectious Diseases 2014 14:52
    Content type: Research article Published on:

  4. Persistent high-risk (HR) human papillomavirus (HPV) infection and increased HR-HPV viral load are associated with the development of cancer. This study investigated the effect of human immunodeficiency virus ...

    Authors: Zizipho ZA Mbulawa, Leigh F Johnson, Dianne J Marais, Inger Gustavsson, Jennifer R Moodley, David Coetzee, Ulf Gyllensten and Anna-Lise Williamson
    Citation: BMC Infectious Diseases 2014 14:51
    Content type: Research article Published on:

  5. Human adenoviruses of species B, C, and E (HAdV-B, –C, -E) are frequent causative agents of acute respiratory infections worldwide. As part of a surveillance program aimed at identifying the etiology of influe...

    Authors: Pola N Demian, Katherine C Horton, Adriana Kajon, Rania Siam, Amel Mohamed Nageib Hasanin, Amany Elgohary Sheta, Claire Cornelius and Anne M Gaynor
    Citation: BMC Infectious Diseases 2014 14:50
    Content type: Research article Published on:

  6. Immunoassays for Plasmodium detection are, presently, most frequently based on monoclonal antibodies (MAbs); Polyclonal antibodies (PAbs), which are cheaper to develop and manufacture, are much less frequently...

    Authors: Luciana Pereira Sousa, Luis André Morais Mariuba, Rudson Jesus Holanda, João Paulo Pimentel, Maria Edilene Martins Almeida, Yury Oliveira Chaves, Davi Borges, Emerson Lima, James Lee Crainey, Patricia Puccinelli Orlandi, Marcus Vinicius Lacerda and Paulo Afonso Nogueira
    Citation: BMC Infectious Diseases 2014 14:49
    Content type: Research article Published on:

  7. ProvLab Alberta provides all laboratory testing for Bordetella pertussis including sporadic cases and outbreak investigations through collaborations with provincial public health partners. We describe B. pertussi...

    Authors: Sumana Fathima, Christina Ferrato, Bonita E Lee, Kimberley Simmonds, Lin Yan, Shamir N Mukhi, Vincent Li, Linda Chui and Steven J Drews
    Citation: BMC Infectious Diseases 2014 14:48
    Content type: Research article Published on:

  8. Klebsiella pneumoniae (KP) expressing hypermucoviscosity phenotype (HV-KP) has abundant capsular polysaccharide (CPS) and is capable of causing invasive syndrome. Sodium salicylate (SAL) reduces the production o...

    Authors: Chen-Hsiang Lee, Lin-Hui Su, Jien-Wei Liu, Chia-Chi Chang, Rong-Fu Chen and Kuender-D Yang
    Citation: BMC Infectious Diseases 2014 14:47
    Content type: Research article Published on:

  9. Streptococcus agalactiae (Group B Streptococcus, GBS), a leading cause of sepsis and meningitis in infants, can be transmitted vertically from mother to infant during passage through the birth canal. Detection o...

    Authors: Toyohisa Morita, Dongyun Feng, Yoko Kamio, Isao Kanno, Teruo Somaya, Kazuhito Imai, Misaki Inoue, Mutsunori Fujiwara and Akihito Miyauchi
    Citation: BMC Infectious Diseases 2014 14:46
    Content type: Research article Published on:

  10. Global efforts to eradicate wild polioviruses (WPVs) continue to face challenges due to uninterrupted endemic WPV transmission in three countries and importation-related outbreaks into previously polio-free co...

    Authors: Radboud J Duintjer Tebbens, Dominika A Kalkowska, Steven GF Wassilak, Mark A Pallansch, Stephen L Cochi and Kimberly M Thompson
    Citation: BMC Infectious Diseases 2014 14:45
    Content type: Research article Published on:

  11. The immunoneuroendocrine axis plays a major role in the regulation of the host’s response to infection, but its role in severe H7N9 pneumonia is still unknown. Therefore, this study is carried out to explore t...

    Authors: Jin Yao, Linhua Liu, Gang Chen and Leng Lin
    Citation: BMC Infectious Diseases 2014 14:44
    Content type: Case report Published on:

  12. Oropharyngeal squamous cell carcinoma (OSCC) has shown a gradual increase in male predominance due to the increasing incidence of human papillomavirus (HPV)-associated OSCC. However, the mode of HPV transmissi...

    Authors: Kazufumi Nakashima, Kazuyoshi Shigehara, Shohei Kawaguchi, Akira Wakatsuki, Yoshitomo Kobori, Kazuyoshi Nakashima, Yasunori Ishii, Masayoshi Shimamura, Toshiyuki Sasagawa, Yasuhide Kitagawa, Atsushi Mizokami and Mikio Namiki
    Citation: BMC Infectious Diseases 2014 14:43
    Content type: Research article Published on:

  13. Yersinia pseudotuberculosis generally infects the gastrointestinal tract and causes enteropathy symptoms suggesting infection. Y. pseudotuberculosis infections are often complicated with intraceliac lymphoadenop...

    Authors: Osamu Imataki, Makiko Uemura, Kensuke Matsumoto and Naoko Ishibashi
    Citation: BMC Infectious Diseases 2014 14:42
    Content type: Case report Published on:

  14. Many cancer patients receive a central venous catheter or port system prior to therapy to assure correct drug administration. Even appropriate hygienic intervention maintenance carries the risk of contaminatin...

    Authors: Fabian Pohl, Werner Hartmann, Thomas Holzmann, Sandra Gensicke, Oliver Kölbl and Matthias G Hautmann
    Citation: BMC Infectious Diseases 2014 14:41
    Content type: Technical advance Published on:

  15. Routine annual influenza vaccination is primarily recommended for all persons aged 60 and above and for people with underlying chronic conditions in Germany. Other countries have already adopted additional chi...

    Authors: Markus A Rose, Oliver Damm, Wolfgang Greiner, Markus Knuf, Peter Wutzler, Johannes G Liese, Hagen Krüger, Ulrich Wahn, Tom Schaberg, Markus Schwehm, Thomas F Kochmann and Martin Eichner
    Citation: BMC Infectious Diseases 2014 14:40
    Content type: Research article Published on:

  16. For patients hospitalised due to community-acquired pneumonia (CAP), mortality risk is usually estimated with prognostic scores such as CRB-65 or CURB-65. For elderly patients, a new score referred to as CURSI...

    Authors: Harald Nüllmann, Marc Andre Pflug, Thomas Wesemann, Hans-Jürgen Heppner, Ludger Pientka and Ulrich Thiem
    Citation: BMC Infectious Diseases 2014 14:39
    Content type: Research article Published on:

  17. Dengue is an increasingly important public health problem in most Latin American countries and more cost-effective ways of reducing dengue vector densities to prevent transmission are in demand by vector contr...

    Authors: Juliana Quintero, Helena Brochero, Pablo Manrique-Saide, Mario Barrera-Pérez, César Basso, Sonnia Romero, Andrea Caprara, Jane Cris De Lima Cunha, Efraín Beltrán - Ayala, Kendra Mitchell-Foster, Axel Kroeger, Johannnes Sommerfeld and Max Petzold
    Citation: BMC Infectious Diseases 2014 14:38
    Content type: Research article Published on:

  18. Reusable surface disinfectant tissue dispensers are used in hospitals in many countries because they allow immediate access to pre-soaked tissues for targeted surface decontamination. On the other hand disinfe...

    Authors: Günter Kampf, Stina Degenhardt, Sibylle Lackner, Katrin Jesse, Heike von Baum and Christiane Ostermeyer
    Citation: BMC Infectious Diseases 2014 14:37
    Content type: Research article Published on:

  20. Dengue fever and leptospirosis have partially overlapping geographic distributions, similar clinical presentations and potentially life-threatening complications but require different treatments. Distinguishin...

    Authors: Andrea L Conroy, Margarita Gélvez, Michael Hawkes, Nimerta Rajwans, W Conrad Liles, Luis Angel Villar-Centeno and Kevin C Kain
    Citation: BMC Infectious Diseases 2014 14:35
    Content type: Research article Published on:

  22. Control programs have been executed in an attempt to reduce vertical transmission and the severity of congenital infection in regions with a high incidence of toxoplasmosis in pregnant women. We aimed to evalu...

    Authors: Mariza M Avelino, Waldemar N Amaral, Isolina MX Rodrigues, Alan R Rassi, Maria BF Gomes, Tatiane L Costa and Ana M Castro
    Citation: BMC Infectious Diseases 2014 14:33
    Content type: Research article Published on:

  23. Reliable assessment for the severity of the 2009 H1N1 pandemic influenza is critical for evaluation of vaccination strategies for future pandemics. This study aims to estimate the age-specific hospitalization ...

    Authors: Xi-Ling Wang, Chit-Ming Wong, Kwok-Hung Chan, King-Pan Chan, Pei-Hua Cao, JS Malik Peiris and Lin Yang
    Citation: BMC Infectious Diseases 2014 14:32
    Content type: Research article Published on:

  24. Previous studies may have overestimated morbidity and mortality due to Klebsiella pneumoniae producing carbapenemase (KPC) Klebsiella pneumoniae infections because of difficulties in modeling patient comorbiditie...

    Authors: Milena M McLaughlin, M Renee Advincula, Michael Malczynski, Grace Barajas, Chao Qi and Marc H Scheetz
    Citation: BMC Infectious Diseases 2014 14:31
    Content type: Research article Published on:

  26. Sporulation of Clostridium difficile during infection and persistence of spores within the gut could partly explain treatment failures and recurrence. However, the influence of antibiotics on sporulation is uncle...

    Authors: Julian R Garneau, Louis Valiquette and Louis-Charles Fortier
    Citation: BMC Infectious Diseases 2014 14:29
    Content type: Research article Published on:

  27. Introduction of antiretroviral therapy (ART) in sub-Saharan Africa was a hot debate due to many concerns about adherence, logistics and resistance. Currently, it has been significantly scaled up. However as th...

    Authors: Andargachew Mulu, Uwe Gerd Liebert and Melanie Maier
    Citation: BMC Infectious Diseases 2014 14:28
    Content type: Research article Published on:

  28. Resistance to carbapenem antibiotics is emerging worldwide among Enterobacteriaceae. To prevent hospital transmission due to unnoticed carriage of carbapenemase producing micro-organisms in newly admitted pati...

    Authors: Anneke van der Zee, Lieuwe Roorda, Gerda Bosman, Ad C Fluit, Mirjam Hermans, Paul HM Smits, Adri GM van der Zanden, René te Witt, Lesla ES Bruijnesteijn van Coppenraet, James Cohen Stuart and Jacobus M Ossewaarde
    Citation: BMC Infectious Diseases 2014 14:27
    Content type: Research article Published on:

  29. Efavirenz (EFV) administration is still controversial for its high rates of interruption mainly related to central nervous system side effects (CNS-SE). Aim of the study was to define if single tablet regimen ...

    Authors: Massimiliano Fabbiani, Mauro Zaccarelli, Pierfrancesco Grima, Mattia Prosperi, Iuri Fanti, Manuela Colafigli, Alessandro D’Avino, Annalisa Mondi, Alberto Borghetti, Massimo Fantoni, Roberto Cauda and Simona Di Giambenedetto
    Citation: BMC Infectious Diseases 2014 14:26
    Content type: Research article Published on:

  30. Cryptosporidium spp., Enterocytozoon spp., Giardia spp. and Cyclospora spp. are important intestinal protozoan parasites causing diarrhea in humans, livestocks and wildlife and have a significant impact on publi...

    Authors: Hua Liu, Yujuan Shen, Jianhai Yin, Zhongying Yuan, Yanyan Jiang, Yuxin Xu, Wei Pan, Yuan Hu and Jianping Cao
    Citation: BMC Infectious Diseases 2014 14:25
    Content type: Research article Published on:

  31. Nutritional changes during and after tuberculosis treatment have not been well described. We therefore determined the effect of wasting on rate of mean change in lean tissue and fat mass as measured by bioelec...

    Authors: Ezekiel Mupere, LaShaunda Malone, Sarah Zalwango, Alphonse Okwera, Mary Nsereko, Daniel J Tisch, Isabel M Parraga, Catherine M Stein, Roy Mugerwa, W Henry Boom, Harriet K Mayanja and Christopher C Whalen
    Citation: BMC Infectious Diseases 2014 14:24
    Content type: Research article Published on:

  32. Patients on anti-tuberculosis treatment may develop acute kidney injury (AKI), but little is known about the renal outcome and prognostic factors, especially in an aging population. This study aimed to calcula...

    Authors: Chia-Hao Chang, Yen-Fu Chen, Vin-Cent Wu, Chin-Chung Shu, Chih-Hsin Lee, Jann-Yuan Wang, Li-Na Lee and Chong-Jen Yu
    Citation: BMC Infectious Diseases 2014 14:23
    Content type: Research article Published on:

  33. Gastrointestinal symptoms, in particular diarrhoea, are common in non-treated HIV-1 infected individuals. Although various enteric pathogens have been implicated, the aetiology of diarrhoea remains unexplained...

    Authors: Bas B Oude Munnink, Marta Canuti, Martin Deijs, Michel de Vries, Maarten F Jebbink, Sjoerd Rebers, Richard Molenkamp, Formijn J van Hemert, Kevin Chung, Matthew Cotten, Fransje Snijders, Cees JA Sol and Lia van der Hoek
    Citation: BMC Infectious Diseases 2014 14:22
    Content type: Research article Published on:

  34. This paper reports findings from the prevalence survey conducted in Shandong China in 2010, a province with a population of 94 million. This study aimed to estimate TB prevalence of the province in 2010 in com...

    Authors: Xiaolin Wei, Xiulei Zhang, Jia Yin, John Walley, Rachel Beanland, Guanyang Zou, Hongmei Zhang, Fang Li, Zhimin Liu, Benny CY Zee and Sian M Griffiths
    Citation: BMC Infectious Diseases 2014 14:21
    Content type: Research article Published on:

  35. Early detection and treatment of TB is essential for the success of TB control program performance. The aim of this study was to determine the length and analyze predictors of patients’, health systems’ and to...

    Authors: Solomon A Yimer, Gunnar A Bjune and Carol Holm-Hansen
    Citation: BMC Infectious Diseases 2014 14:19
    Content type: Research article Published on:

  36. Rifampicin resistance is a risk factor for poor outcome in tuberculosis. Therefore, we sought to describe the characteristics and management of Rifampicin monoresistant (RMR) tuberculosis (TB) in France.

    Authors: Vanina Meyssonnier, Thuy Van Bui, Nicolas Veziris, Vincent Jarlier and Jérôme Robert
    Citation: BMC Infectious Diseases 2014 14:18
    Content type: Research article Published on:

  38. A limitation of both culture-based and molecular methods of screening for staphylococcal infection is that current tests determine only the presence or absence of colonization with no information on the coloni...

    Authors: Aleksandar Kecojevic, Ray Ranken, David J Ecker, Christian Massire, Rangarajan Sampath, Lawrence B Blyn, Yu-Hsiang Hsieh, Richard E Rothman and Charlotte A Gaydos
    Citation: BMC Infectious Diseases 2014 14:16
    Content type: Research article Published on:

  39. Carefully conducted, community-based, longitudinal studies are required to gain further understanding of the nature and timing of respiratory viruses causing infections in the population. However, such studies...

    Authors: Asma N Alsaleh, David M Whiley, Seweryn Bialasiewicz, Stephen B Lambert, Robert S Ware, Michael D Nissen, Theo P Sloots and Keith Grimwood
    Citation: BMC Infectious Diseases 2014 14:15
    Content type: Research article Published on:

  40. There is urgent need for effective HIV prevention methods that women can initiate. The CAPRISA 004 trial showed that a tenofovir-based vaginal microbicide had significant impact on HIV incidence among women. T...

    Authors: Fern Terris-Prestholt, Anna M Foss, Andrew P Cox, Lori Heise, Gesine Meyer-Rath, Sinead Delany-Moretlwe, Thomas Mertenskoetter, Helen Rees, Peter Vickerman and Charlotte H Watts
    Citation: BMC Infectious Diseases 2014 14:14
    Content type: Research article Published on:

  41. Greater use of antibiotics during the past 50 years has exerted selective pressure on susceptible bacteria and may have favoured the survival of resistant strains. Existing information on antibiotic resistance...

    Authors: Brian G Bell, Francois Schellevis, Ellen Stobberingh, Herman Goossens and Mike Pringle
    Citation: BMC Infectious Diseases 2014 14:13
    Content type: Research article Published on:

  43. In drug-resistant TB settings, specimen collection is critical for drug-susceptibility testing (DST). This observational study included multiple specimen types collected from pediatric TB suspects with the aim...

    Authors: Tania A Thomas, Scott K Heysell, Prashini Moodley, Romualde Montreuil, Xia Ha, Gerald Friedland, Sheila A Bamber, Anthony P Moll, Neel Gandhi, William E Brant, Willem Sturm and Sarita Shah
    Citation: BMC Infectious Diseases 2014 14:11
    Content type: Research article Published on:

  44. There have been few studies of pulmonary actinomycosis, which is an uncommon anaerobic infection. Consequently, the optimal therapeutic regimen, appropriate duration of treatment, long-term prognosis, and fact...

    Authors: Ji Young Park, Taehoon Lee, Hongyeul Lee, Hyo-Jeong Lim, Jinwoo Lee, Jong Sun Park, Young-Jae Cho, Young Sik Park, Chang-Hoon Lee, Sang-Min Lee, Ho Il Yoon, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Choon-Taek Lee…
    Citation: BMC Infectious Diseases 2014 14:10
    Content type: Research article Published on:

  45. Although extrapulmonary tuberculosis (EPTB) is less frequent than Pulmonary Tuberculosis (PTB) and is a secondary target for national TB control programs, its significance has increased worldwide during the HI...

    Authors: Teresa Gomes, Bárbara Reis-Santos, Adelmo Bertolde, John L Johnson, Lee W Riley and Ethel Leonor Maciel
    Citation: BMC Infectious Diseases 2014 14:9
    Content type: Research article Published on:

  46. HIV is the top and tuberculosis is the second leading cause of death from infectious disease worldwide, with an estimated 8.7 million incident cases of tuberculosis and 2.5 million new HIV infections annually. Th...

    Authors: Elisabetta Venturini, Anna Turkova, Elena Chiappini, Luisa Galli, Maurizio de Martino and Claire Thorne
    Citation: BMC Infectious Diseases 2014 14(Suppl 1):S5
    Content type: Review Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  47. The ongoing spread of tuberculosis (TB) in poor resource countries and the recently increasing incidence in high resource countries lead to the need of updated knowledge for clinicians, particularly for pediat...

    Authors: Paola Piccini, Elena Chiappini, Enrico Tortoli, Maurizio de Martino and Luisa Galli
    Citation: BMC Infectious Diseases 2014 14(Suppl 1):S4
    Content type: Review Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  48. Paediatric tuberculosis (TB) represents a major public health concern worldwide. About 1 million children aged less than 15 years develop TB each year, contributing to 3-25% of the total TB caseload. The aim o...

    Authors: Elettra Berti, Luisa Galli, Elisabetta Venturini, Maurizio de Martini and Elena Chiappini
    Citation: BMC Infectious Diseases 2014 14(Suppl 1):S3
    Content type: Review Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  49. one of the World Health Organization Millennium Development Goal is to reduce tuberculosis incidence by 2015. However, more of 8.5 million tuberculosis cases have been reported in 2011, with an increase of mul...

    Authors: Carlotta Montagnani, Elena Chiappini, Luisa Galli and Maurizio de Martino
    Citation: BMC Infectious Diseases 2014 14(Suppl 1):S2
    Content type: Review Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  50. Many and large dumps exist in our knowledge about Mycobacterium tuberculosis infection and disease in infants and children. We still do not understand why some individuals do acquire and others do not acquire the...

    Authors: Maurizio de Martino, Luisa Galli and Elena Chiappini
    Citation: BMC Infectious Diseases 2014 14(Suppl 1):S1
    Content type: Review Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

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